Cap-aspiration lumpectomy for small submucosal tumors originating from the muscularis propria of the gastric fundus: a preliminary study (with videos)

• Published in: Journal of digestive diseases 2015-11, Vol.16 (11), p.642-648
• Main Authors: Qiao, Wei Guang, Ren, Yu Tang, Gong, Wei, Jiang, Bo, Liu, Si De, Zhou, Dan, Li, Jing, Xing, Tong Yin, Bai, Yang, Zhi, Fa Chao
• Format: Article
• Language: English
• Subjects: Adult; Aged; cap-aspiration lumpectomy; Feasibility Studies; Female; Gastrectomy - adverse effects; Gastrectomy - methods; Gastric Fundus; Gastric Mucosa; Humans; Male; Middle Aged; Muscle, Smooth; muscularis propria; Neoplasm Staging; Postoperative Care - methods; Stomach Neoplasms - pathology; Stomach Neoplasms - surgery; submucosal tumor; Suction - adverse effects; Suction - methods; Treatment Outcome; Tumors
• ISSN: 1751-2972; 1751-2980
• DOI: 10.1111/1751-2980.12292

Objective Small fundal submucosal tumors (SMTs) originated from the muscularis propria pose great difficulties to conventional therapies. We aimed to evaluate the feasibility and safety of endoscopic cap‐aspiration lumpectomy (CASL) as a new and simple full‐thickness resection for the treatment of small fundal SMTs. Methods From July 2013 to February 2014, patients with small fundal SMTs of ≤10 mm in diameter that were originated from muscularis propria were included in the study. CASL was performed by suctioning SMTs into a transparent cap, ligating with a metal snare and resecting the tumors. The wall deficit was closed by using endoclips. Results Altogether 28 patients were included in the study. CASL achieved an en bloc resection rate of 100%, with a mean total procedure time of 23.9 min. Active perforation was found in 20 (71.4%) patients, and endoclips closed the wall defect in all 20 cases. One patient developed pneumoperitoneum and self‐limited peritonitis was found in two patients, all of whom were managed successfully. Pathological examination showed that 71.4% (20/28) of the tumors were gastrointestinal stromal tumors. No tumor recurrence was observed during the follow‐up. ConclusionS CASL may be a feasible and safe full‐thickness resection modality for the treatment of small fundal SMTs arising from the muscularis propria. Further randomized studies are needed to confirm the results.