Features of cyclic sleep organization and melatonin production in full-term newborns with intrauterine growth retardation

Data on the formation of cyclic sleep organization and melatonin production in full-term newborn infants with intrauterine growth retardation (IUGR) are presented. It has been shown that disordered cyclic sleep organization in IUGR newborns indicates the degree of intrauterine brain damage as a resu...

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Bibliographic Details
Published in:Human physiology 2013-11, Vol.39 (6), p.617-624
Main Authors: Evsyukova, I. I., Koval’chuk-Kovalevskaya, O. V., Maslyanyuk, N. A., Dodkhoev, D. S.
Format: Article
Language:English
Subjects:
Biomedical and Life Sciences
Biomedicine
Brain damage
Human
Human Physiology
Infants
Life Sciences
Melatonin
Organizations
Phase (cyclic)
Reflexes
Sleep
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Summary:Data on the formation of cyclic sleep organization and melatonin production in full-term newborn infants with intrauterine growth retardation (IUGR) are presented. It has been shown that disordered cyclic sleep organization in IUGR newborns indicates the degree of intrauterine brain damage as a result of chronic hypoxia. The absence of cyclic sleep organization, the disordered formation of the paradoxical phase combined with delayed development of tonic, congenital reflex reactions, and low melatonin production give evidence of severe brain damage, which warrants combined therapy in the early neonatal period of life.
ISSN:0362-1197
1608-3164
DOI:10.1134/S0362119713060030