Association between subthalamic nucleus deep brain stimulation and weight gain: Results of a case–control study

Highlights • Patients with PD have been shown to lose weight over the course of their disease. • Weight gain has been reported in PD patients after deep brain stimulation (DBS). • In this study, PD cases gained weight while controls not undergoing DBS lost weight. • This weight gain may be normative...

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2016-01, Vol.140, p.38-42
Main Authors: Strowd, Roy E, Herco, Maja, Passmore-Griffin, Leah, Avery, Bradley, Haq, Ihtsham, Tatter, Stephen B, Tate, Jessica, Siddiqui, Mustafa S
Format: Article
Language:English
Subjects:
Age
Aged
Body composition
Body mass index
Case-Control Studies
Case–control study
Confidence intervals
Deep brain stimulation
Deep Brain Stimulation - adverse effects
Deep Brain Stimulation - methods
Disease prevention
Female
Funding
Gender
Health sciences
Humans
Male
Middle Aged
Neurology
Neurosurgery
Parkinson Disease - physiopathology
Parkinson Disease - therapy
Parkinson's disease
Retrospective Studies
Standard deviation
Subthalamic nucleus
Subthalamic Nucleus - surgery
Treatment Outcome
Weight gain
Weight Gain - physiology
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Summary:Highlights • Patients with PD have been shown to lose weight over the course of their disease. • Weight gain has been reported in PD patients after deep brain stimulation (DBS). • In this study, PD cases gained weight while controls not undergoing DBS lost weight. • This weight gain may be normative and further prospective study is needed.
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2015.11.002