Phenytoin poisoning after using Chinese proprietary medicines

We report a case of poisoning resulting from the use of Chinese proprietary medicines (CPM) containing antic-onvulsants phenytoin, carbamazepine and valproate. The manufacturer's information leaflets did not mention any of these prescription drugs. As a consequence, the patient was admitted com...

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Bibliographic Details
Published in:Human & experimental toxicology 2000-07, Vol.19 (7), p.385-386
Main Authors: Lau, K K, Lai, C K, Chan, A YW
Format: Article
Language:English
Subjects:
Adult
Anticonvulsants - poisoning
Biological and medical sciences
Carbamazepine - poisoning
Drug Combinations
Drug Contamination
Drug intoxications. Doping
Drugs, Chinese Herbal - poisoning
Female
herbal medicines
Humans
Medical sciences
Pharmacology. Drug treatments
Phenytoin - poisoning
Valproic Acid - poisoning
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Summary:We report a case of poisoning resulting from the use of Chinese proprietary medicines (CPM) containing antic-onvulsants phenytoin, carbamazepine and valproate. The manufacturer's information leaflets did not mention any of these prescription drugs. As a consequence, the patient was admitted comatose due to severe phenytoin poisoning. We are not aware of any reported case of severe poisoning due to CPM adulterated with anticonvulsants and this is possibly the first case.
ISSN:0960-3271
1477-0903
DOI:10.1191/096032700678816115