Fibromyxoid nephrogenic adenoma protruding in a renal cortical cyst. A rare morphological variant in an outstanding location

Nephrogenic adenoma (NA) is an unusual, benign lesion of the urinary tract, generally presenting in the bladder and with less frequency in the renal pelvis, urethra or ureter. It consists of tubules, microcysts and papillae lined by a single layer of low cuboidal epithelium without atypia. Recently,...

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Bibliographic Details
Published in:Pathology, research and practice research and practice, 2016-02, Vol.212 (2), p.135-138
Main Authors: Khedaoui, Radia, Encabo, Beatriz, Tardío, Juan C.
Format: Article
Language:English
Subjects:
Adenoma - chemistry
Adenoma - pathology
Adenoma - surgery
Aged
Biomarkers, Tumor - analysis
Biopsy
Female
Fibromyxoid nephrogenic adenoma
Humans
Immunohistochemistry
Kidney Cortex - chemistry
Kidney Cortex - pathology
Kidney Cortex - surgery
Kidney Diseases, Cystic - pathology
Kidney Diseases, Cystic - surgery
Kidney Neoplasms - chemistry
Kidney Neoplasms - pathology
Kidney Neoplasms - surgery
Laparoscopy
Nephrectomy - methods
Nephrogenic adenoma
Renal cortical cyst
Renal tumor
Treatment Outcome
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Description
Summary:Nephrogenic adenoma (NA) is an unusual, benign lesion of the urinary tract, generally presenting in the bladder and with less frequency in the renal pelvis, urethra or ureter. It consists of tubules, microcysts and papillae lined by a single layer of low cuboidal epithelium without atypia. Recently, a fibromyxoid variant mimicking an infiltrating mucinous adenocarcinoma has been described. We report hereby the case of a 70-year-old female with a fibromixoid NA protruding in a renal cortical cyst. Only one case of NA in a renal cortical cyst has been found in the literature and it was of the classical type. The development of a NA in a renal cortical cyst lends support to the theory that the NA results from proliferation of secondarily implanted exfoliated renal epithelial cells.
ISSN:0344-0338
1618-0631
DOI:10.1016/j.prp.2015.09.013