Relationship between obstructive sleep apnea cardiac complications and sleepiness in children with Down syndrome

Highlights • Children with Down syndrome underwent polysomnography and echocardiography. • Those with obstructive sleep apnea (OSA) were randomized to actual or sham continuous positive airway pressure (CPAP). • Subjects had a high rate of OSA, despite previous adenotonsillectomy. • There was a low...

Full description

Saved in:
Bibliographic Details
Published in:Sleep medicine 2016-01, Vol.17, p.18-24
Main Authors: Konstantinopoulou, Sofia, Tapia, Ignacio E, Kim, Ji Young, Xanthopoulos, Melissa S, Radcliffe, Jerilynn, Cohen, Meryl S, Hanna, Brian D, Pipan, Mary, Cielo, Christopher, Thomas, Allison J, Zemel, Babette, Amin, Raouf, Bradford, Ruth, Traylor, Joel, Shults, Justine, Marcus, Carole L
Format: Article
Language:English
Subjects:
Adolescent
Cardiovascular Diseases - etiology
Child
Continuous Positive Airway Pressure
Down syndrome
Down Syndrome - complications
Female
Humans
Male
Neurology
Noninvasive ventilation
Polysomnography
Sleep Apnea, Obstructive - complications
Sleep Apnea, Obstructive - physiopathology
Sleep Apnea, Obstructive - therapy
Sleep Medicine
Sleep Wake Disorders - etiology
Sleep-disordered breathing
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • Children with Down syndrome underwent polysomnography and echocardiography. • Those with obstructive sleep apnea (OSA) were randomized to actual or sham continuous positive airway pressure (CPAP). • Subjects had a high rate of OSA, despite previous adenotonsillectomy. • There was a low rate of pulmonary hypertension. • Diastolic dysfunction correlated with OSA severity and improved with CPAP.
ISSN:1389-9457
1878-5506
DOI:10.1016/j.sleep.2015.09.014