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Residual low ADC and high FA at the resection margin correlate with poor chemoradiation response and overall survival in high-grade glioma patients
Highlights • Resection margin ADC (rmADC) correlates with survival in HGG patients. • Low rmADC correlates with shorter overall survival. • rmADC correlation with survival is stronger in non-enhancing than enhancing tumor. • Pre- chemoradiation ADC correlates better with OS than change in ADC during...
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Published in: | European journal of radiology 2016-03, Vol.85 (3), p.657-664 |
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container_title | European journal of radiology |
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creator | Qu, Jinrong Qin, Lei Cheng, Suchun Leung, Katherine Li, Xiang Li, Hailiang Dai, Jianping Jiang, Tao Akgoz, Ayca Seethamraju, Ravi Wang, Qifeng Rahman, Rifaquat Li, Shaowu Ai, Lin Jiang, Tianzi Young, Geoffrey S |
description | Highlights • Resection margin ADC (rmADC) correlates with survival in HGG patients. • Low rmADC correlates with shorter overall survival. • rmADC correlation with survival is stronger in non-enhancing than enhancing tumor. • Pre- chemoradiation ADC correlates better with OS than change in ADC during RT. |
doi_str_mv | 10.1016/j.ejrad.2015.12.026 |
format | article |
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Qin, Lei ; Cheng, Suchun ; Leung, Katherine ; Li, Xiang ; Li, Hailiang ; Dai, Jianping ; Jiang, Tao ; Akgoz, Ayca ; Seethamraju, Ravi ; Wang, Qifeng ; Rahman, Rifaquat ; Li, Shaowu ; Ai, Lin ; Jiang, Tianzi ; Young, Geoffrey S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c414t-ad0f1bb524e8634feb1534e7bfb74be4dd170fc16309e9c25037030089820b2b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Apparent diffusion coefficient</topic><topic>Area Under Curve</topic><topic>Astrocytoma - pathology</topic><topic>Astrocytoma - therapy</topic><topic>Chemoradiotherapy - methods</topic><topic>Dacarbazine - analogs & derivatives</topic><topic>Dacarbazine - therapeutic use</topic><topic>Female</topic><topic>Fractional anisotropy</topic><topic>Glioblastoma - pathology</topic><topic>Glioblastoma - therapy</topic><topic>High grade glioma</topic><topic>Humans</topic><topic>Magnetic resonance imaging</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Radiology</topic><topic>ROC Curve</topic><topic>Survival Analysis</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Qu, Jinrong</creatorcontrib><creatorcontrib>Qin, Lei</creatorcontrib><creatorcontrib>Cheng, Suchun</creatorcontrib><creatorcontrib>Leung, Katherine</creatorcontrib><creatorcontrib>Li, Xiang</creatorcontrib><creatorcontrib>Li, Hailiang</creatorcontrib><creatorcontrib>Dai, Jianping</creatorcontrib><creatorcontrib>Jiang, Tao</creatorcontrib><creatorcontrib>Akgoz, Ayca</creatorcontrib><creatorcontrib>Seethamraju, Ravi</creatorcontrib><creatorcontrib>Wang, Qifeng</creatorcontrib><creatorcontrib>Rahman, Rifaquat</creatorcontrib><creatorcontrib>Li, Shaowu</creatorcontrib><creatorcontrib>Ai, Lin</creatorcontrib><creatorcontrib>Jiang, Tianzi</creatorcontrib><creatorcontrib>Young, Geoffrey S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Qu, Jinrong</au><au>Qin, Lei</au><au>Cheng, Suchun</au><au>Leung, Katherine</au><au>Li, Xiang</au><au>Li, Hailiang</au><au>Dai, Jianping</au><au>Jiang, Tao</au><au>Akgoz, Ayca</au><au>Seethamraju, Ravi</au><au>Wang, Qifeng</au><au>Rahman, Rifaquat</au><au>Li, Shaowu</au><au>Ai, Lin</au><au>Jiang, Tianzi</au><au>Young, Geoffrey S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Residual low ADC and high FA at the resection margin correlate with poor chemoradiation response and overall survival in high-grade glioma patients</atitle><jtitle>European journal of radiology</jtitle><addtitle>Eur J Radiol</addtitle><date>2016-03-01</date><risdate>2016</risdate><volume>85</volume><issue>3</issue><spage>657</spage><epage>664</epage><pages>657-664</pages><issn>0720-048X</issn><eissn>1872-7727</eissn><abstract>Highlights • Resection margin ADC (rmADC) correlates with survival in HGG patients. • Low rmADC correlates with shorter overall survival. • rmADC correlation with survival is stronger in non-enhancing than enhancing tumor. • Pre- chemoradiation ADC correlates better with OS than change in ADC during RT.</abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>26860681</pmid><doi>10.1016/j.ejrad.2015.12.026</doi><tpages>8</tpages></addata></record> |
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subjects | Apparent diffusion coefficient Area Under Curve Astrocytoma - pathology Astrocytoma - therapy Chemoradiotherapy - methods Dacarbazine - analogs & derivatives Dacarbazine - therapeutic use Female Fractional anisotropy Glioblastoma - pathology Glioblastoma - therapy High grade glioma Humans Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Middle Aged Radiology ROC Curve Survival Analysis Treatment Outcome |
title | Residual low ADC and high FA at the resection margin correlate with poor chemoradiation response and overall survival in high-grade glioma patients |
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