Insulin resistance: The linchpin between prediabetes and cardiovascular disease

The aim of this study was to test the hypothesis that cardiovascular disease occurs to the greatest extent in persons with prediabetes mellitus who are also insulin resistant. In 2003, 664 non-diabetic women (n = 457) and men (n = 207), aged 52 ± 16 and 53 ± 15 years, were surveyed during a programm...

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Bibliographic Details
Published in:Diabetes & vascular disease research 2016-03, Vol.13 (2), p.157-163
Main Authors: Salazar, Martin R, Carbajal, Horacio A, Espeche, Walter G, Aizpurúa, Marcelo, Leiva Sisnieguez, Carlos E, Leiva Sisnieguez, Betty C, Stavile, Rodolfo N, March, Carlos E, Reaven, Gerald M
Format: Article
Language:English
Subjects:
Adult
Aged
Blood Glucose - analysis
Cardiovascular Diseases - complications
Cardiovascular Diseases - epidemiology
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - epidemiology
Fasting
Female
Glucose Tolerance Test
Humans
Incidence
Insulin - blood
Insulin Resistance - physiology
Male
Middle Aged
Prediabetic State - blood
Proportional Hazards Models
Risk
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Summary:The aim of this study was to test the hypothesis that cardiovascular disease occurs to the greatest extent in persons with prediabetes mellitus who are also insulin resistant. In 2003, 664 non-diabetic women (n = 457) and men (n = 207), aged 52 ± 16 and 53 ± 15 years, were surveyed during a programme for cardiovascular disease prevention. Fasting plasma glucose concentrations defined participants as having normal fasting plasma glucose (fasting plasma glucose
ISSN:1479-1641
1752-8984
DOI:10.1177/1479164115610057