Prophylactic dexamethasone for radiation-induced bone-pain flare – Authors' reply

Testing for benefits, especially the safety of prophylactic dexamethasone in patients already prescribed NSAIDs, could be an important future question. Because of the short half-life of dexamethasone, we deemed the quality of life and adverse event data that we reported at day 10, 5 days after compl...

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Bibliographic Details
Published in:The lancet oncology 2016-02, Vol.17 (2), p.e40-e41
Main Authors: Chow, Edward, Meyer, Ralph M, Ding, Keyue, Nabid, Abdenour, Chabot, Pierre, Wong, Philip, Ahmed, Shahida, Kuk, Joda, Dar, A Rashid, Mahmud, Aamer, Fairchild, Alysa, Wilson, Carolyn F, Wu, Jackson S Y, Dennis, Kristopher, Brundage, Michael, DeAngelis, Carlo, Wong, Rebecca K S
Format: Article
Language:English
Subjects:
Bone Neoplasms - radiotherapy
Bone Neoplasms - secondary
Dexamethasone
Dexamethasone - therapeutic use
Female
Glucocorticoids - therapeutic use
Hematology, Oncology and Palliative Medicine
Humans
Male
Pain
Pain - prevention & control
Pain management
Palliative Care
Prescription drugs
Quality of life
Side effects
Citations: Items that this one cites
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Summary:Testing for benefits, especially the safety of prophylactic dexamethasone in patients already prescribed NSAIDs, could be an important future question. Because of the short half-life of dexamethasone, we deemed the quality of life and adverse event data that we reported at day 10, 5 days after completing prophylactic dexamethasone, as best showing the effect of the drug on these endpoints.
ISSN:1470-2045
1474-5488
DOI:10.1016/S1470-2045(16)00029-2