New Polyketides from the Sponge Plakortis sp

Fractionation of the MeOH extract of the sponge Plakortis sp. collected around the Amirantes Islands yielded four novel polyketides (4−7). The structures have been established by a detailed highfield 2D NMR study.

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 1998-08, Vol.61 (8), p.1038-1042
Main Authors: Braekman, J. C, Daloze, D, De Groote, S, Fernandes, J. B, Van Soest, R. W. M
Format: Article
Language:English
Subjects:
Animals
Antineoplastic Agents - isolation & purification
Antineoplastic Agents - pharmacology
Antineoplastic Agents - toxicity
Artemia
Biological and medical sciences
Dioxanes - isolation & purification
Dioxanes - pharmacology
Dioxanes - toxicity
Drug Screening Assays, Antitumor
Furans - isolation & purification
Furans - pharmacology
Furans - toxicity
General pharmacology
Lethal Dose 50
Magnetic Resonance Spectroscopy
Marine
Mass Spectrometry
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plakortis
Porifera - chemistry
Spectrophotometry, Infrared
Spectrophotometry, Ultraviolet
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Description
Summary:Fractionation of the MeOH extract of the sponge Plakortis sp. collected around the Amirantes Islands yielded four novel polyketides (4−7). The structures have been established by a detailed highfield 2D NMR study.
ISSN:0163-3864
1520-6025
DOI:10.1021/np980096z