Improving the performance of reflex Human Papilloma Virus (HPV) testing in triaging women with atypical squamous cells of undetermined significance (ASCUS): A restrospective study in a tertiary hospital in United Arab Emirates (UAE)

Highlights • In our study, High Risk Human Papilloma Virus (HR-HPV) prevalence was higher among premenopausal women compared to postmenopausal women. • The rate of progression to high grade lesions was also higher in the premenopausal group compared to the postmenopausal group. • Reflex HPV testing...

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Bibliographic Details
Published in:Vaccine 2016-02, Vol.34 (6), p.823-830
Main Authors: Fakhreldin, Marwa, Elmasry, Karim
Format: Article
Language:English
Subjects:
Adult
Age
Aged
Allergy and Immunology
Atypical Squamous Cells of the Cervix
Atypical squamous cells of undetermined significance
Cervical cancer
Cervical screening
Conflicts of interest
Deoxyribonucleic acid
DNA
Female
Funding
Genetic testing
High Risk Human Papilloma Virus
Human papillomavirus
Humans
Laboratories
Lesions
Middle Aged
Mortality
Papanicolaou Test - standards
Papillomaviridae - classification
Papillomavirus Infections - diagnosis
Patients
Postmenopause
Premenopause
Prevalence
Reflex HPV testing
Risk factors
Sensitivity and Specificity
Tertiary Care Centers
Triage of ASCUS
United Arab Emirates
Uterine Cervical Neoplasms - diagnosis
Uterine Cervical Neoplasms - virology
Vaginal Smears
Womens health
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Description
Summary:Highlights • In our study, High Risk Human Papilloma Virus (HR-HPV) prevalence was higher among premenopausal women compared to postmenopausal women. • The rate of progression to high grade lesions was also higher in the premenopausal group compared to the postmenopausal group. • Reflex HPV testing can triage ASCUS cases more efficiently upon combining multiple assessment parameters.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2015.12.011