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Serum 25-Hydroxyvitamin D associated with indicators of body fat and insulin resistance in prepubertal chilean children
Background: Consistent data on the relation between vitamin D, body fat and insulin resistance (IR) in children are lacking. Objectives: (1) To evaluate the association between serum 25-Hydroxyvitamin D [25(OH)D] and key indicators of: adiposity (total and central), IR, and (2) to estimate serum 25(...
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| Published in: | International Journal of Obesity 2016-01, Vol.40 (1), p.147-152 |
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| container_end_page | 152 |
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| container_title | International Journal of Obesity |
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| creator | Cediel, G Corvalán, C Aguirre, C de Romaña, D L Uauy, R |
| description | Background:
Consistent data on the relation between vitamin D, body fat and insulin resistance (IR) in children are lacking.
Objectives:
(1) To evaluate the association between serum 25-Hydroxyvitamin D [25(OH)D] and key indicators of: adiposity (total and central), IR, and (2) to estimate serum 25(OH)D cut-offs that best reflect IR and total and central adiposity in children.
Subjects/Methods:
Prepubertal children (
n
=435, ~53% girls; ~age 7 years) from the Growth and Obesity Chilean Cohort Study were evaluated for potential associations between serum 25(OH)D and indicators of: (1) total adiposity (body mass index by age (BAZ), body fat (including three-component model)), central adiposity (waist circumference and trunk fatness); (2) IR (homeostasis model assessment of IR) and insulin sensitive (quantitative insulin sensitivity check index) using standardized multiple regression models with standardized coefficients and receiver operating characteristic curves.
Results:
Overall, mean serum 25(OH)D was 32.1±9.2 ng ml
−1
, while 19.4% of children were obese (BAZ⩾2 s.d.). Serum 25(OH)D was inversely associated with indicators of total and central adiposity and with IR indicators. Effect sizes were moderate in girls (~0.3 for adiposity and IR indicators), while, weaker values were found in boys. Serum 25(OH)D estimated cut-offs that best predicted total, central adiposity and IR were~30 ng ml
−1
. Children with suboptimal serum 25(OH)D ( |
| doi_str_mv | 10.1038/ijo.2015.148 |
| format | article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1765981571</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A440058360</galeid><sourcerecordid>A440058360</sourcerecordid><originalsourceid>FETCH-LOGICAL-c596t-1dafd73aad3341b1169935d8d85766e254b4664128de7fabf99c19cce732bdf3</originalsourceid><addsrcrecordid>eNqNks1rFTEUxYMotlZ3riUgiAvnme_MLEv9qFBwYfdDJrnTl8dM8kwy1vffm9dXtZUuJIsLub9z4CQHoZeUrCjh7Xu_iStGqFxR0T5Cx1Ro1UjR6cfomHCiGyKVPELPct4QQqQk7Ck6YoopoaU-RtffIC0zZrI537kUf-5--GJmH_AHbHKO1psCDl_7ssY-OG9NiSnjOOIhuh0eTcEmuLrKy1RFCbLPxQQL9QpvE2yXAVIxE7ZrP4EJN9MlCM_Rk9FMGV7czhN0-enj5dl5c_H185ez04vGyk6VhjozOs2NcZwLOlCquo5L17pWaqWASTEIpQRlrQM9mmHsOks7a0FzNriRn6C3B9ttit8XyKWffbYwTSZAXHJPtZJdS6Wm_4FKQdquE21FX_-DbuKSQs2xpzhjilP9l7oyE_Q-jLEkY_em_akQ9S9arkilVg9Q9TiYvY0Bxvpw9wVv7gjWYKayznFaio8h3wffHUCbYs4Jxn6b_GzSrqek31enr9Xp99Xp6U2oV7ehlmEG9wf-3ZUKNAcg11W4gnQn9UOGvwD66svw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1753226317</pqid></control><display><type>article</type><title>Serum 25-Hydroxyvitamin D associated with indicators of body fat and insulin resistance in prepubertal chilean children</title><source>Nature Publishing Group</source><source>Springer Link</source><creator>Cediel, G ; Corvalán, C ; Aguirre, C ; de Romaña, D L ; Uauy, R</creator><creatorcontrib>Cediel, G ; Corvalán, C ; Aguirre, C ; de Romaña, D L ; Uauy, R</creatorcontrib><description>Background:
Consistent data on the relation between vitamin D, body fat and insulin resistance (IR) in children are lacking.
Objectives:
(1) To evaluate the association between serum 25-Hydroxyvitamin D [25(OH)D] and key indicators of: adiposity (total and central), IR, and (2) to estimate serum 25(OH)D cut-offs that best reflect IR and total and central adiposity in children.
Subjects/Methods:
Prepubertal children (
n
=435, ~53% girls; ~age 7 years) from the Growth and Obesity Chilean Cohort Study were evaluated for potential associations between serum 25(OH)D and indicators of: (1) total adiposity (body mass index by age (BAZ), body fat (including three-component model)), central adiposity (waist circumference and trunk fatness); (2) IR (homeostasis model assessment of IR) and insulin sensitive (quantitative insulin sensitivity check index) using standardized multiple regression models with standardized coefficients and receiver operating characteristic curves.
Results:
Overall, mean serum 25(OH)D was 32.1±9.2 ng ml
−1
, while 19.4% of children were obese (BAZ⩾2 s.d.). Serum 25(OH)D was inversely associated with indicators of total and central adiposity and with IR indicators. Effect sizes were moderate in girls (~0.3 for adiposity and IR indicators), while, weaker values were found in boys. Serum 25(OH)D estimated cut-offs that best predicted total, central adiposity and IR were~30 ng ml
−1
. Children with suboptimal serum 25(OH)D (<30 ng ml
−1
) had a higher risk (two to three times) of being obese (high BAZ, body fat percent and/or central adiposity); and three to four times greater risk for IR.
Conclusions:
Serum 25(OH)D was inversely associated with adiposity (total and central) and IR indicators in prepubertal Chilean children. The conventional cut-off of vitamin D sufficiency (⩾30 ng ml
−1
) was adequate to assess obesity and IR risk in this age group.</description><identifier>ISSN: 0307-0565</identifier><identifier>EISSN: 1476-5497</identifier><identifier>DOI: 10.1038/ijo.2015.148</identifier><identifier>PMID: 26264757</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/308/174 ; 692/499 ; 692/53 ; 692/699/317 ; 692/700/1720 ; 82 ; 82/51 ; Adiposity ; Age ; Analysis ; Body Composition ; Body fat ; Body Mass Index ; Care and treatment ; Child ; Children ; Children & youth ; Chile - epidemiology ; Cohort analysis ; Epidemiology ; Female ; Follow-Up Studies ; Food science ; Health aspects ; Health Promotion and Disease Prevention ; Humans ; Insulin Resistance ; Internal Medicine ; Longitudinal Studies ; Male ; Medicine ; Medicine & Public Health ; Metabolic Diseases ; Metabolism ; Nutrition ; Obesity ; Obesity, Abdominal - blood ; Obesity, Abdominal - epidemiology ; Obesity, Abdominal - etiology ; original-article ; Public Health ; Standard scores ; Vitamin D ; Vitamin D - analogs & derivatives ; Vitamin D - blood ; Vitamin D Deficiency - blood ; Vitamin D Deficiency - complications ; Vitamin D Deficiency - epidemiology</subject><ispartof>International Journal of Obesity, 2016-01, Vol.40 (1), p.147-152</ispartof><rights>Macmillan Publishers Limited 2016</rights><rights>COPYRIGHT 2016 Nature Publishing Group</rights><rights>Copyright Nature Publishing Group Jan 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c596t-1dafd73aad3341b1169935d8d85766e254b4664128de7fabf99c19cce732bdf3</citedby><cites>FETCH-LOGICAL-c596t-1dafd73aad3341b1169935d8d85766e254b4664128de7fabf99c19cce732bdf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26264757$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cediel, G</creatorcontrib><creatorcontrib>Corvalán, C</creatorcontrib><creatorcontrib>Aguirre, C</creatorcontrib><creatorcontrib>de Romaña, D L</creatorcontrib><creatorcontrib>Uauy, R</creatorcontrib><title>Serum 25-Hydroxyvitamin D associated with indicators of body fat and insulin resistance in prepubertal chilean children</title><title>International Journal of Obesity</title><addtitle>Int J Obes</addtitle><addtitle>Int J Obes (Lond)</addtitle><description>Background:
Consistent data on the relation between vitamin D, body fat and insulin resistance (IR) in children are lacking.
Objectives:
(1) To evaluate the association between serum 25-Hydroxyvitamin D [25(OH)D] and key indicators of: adiposity (total and central), IR, and (2) to estimate serum 25(OH)D cut-offs that best reflect IR and total and central adiposity in children.
Subjects/Methods:
Prepubertal children (
n
=435, ~53% girls; ~age 7 years) from the Growth and Obesity Chilean Cohort Study were evaluated for potential associations between serum 25(OH)D and indicators of: (1) total adiposity (body mass index by age (BAZ), body fat (including three-component model)), central adiposity (waist circumference and trunk fatness); (2) IR (homeostasis model assessment of IR) and insulin sensitive (quantitative insulin sensitivity check index) using standardized multiple regression models with standardized coefficients and receiver operating characteristic curves.
Results:
Overall, mean serum 25(OH)D was 32.1±9.2 ng ml
−1
, while 19.4% of children were obese (BAZ⩾2 s.d.). Serum 25(OH)D was inversely associated with indicators of total and central adiposity and with IR indicators. Effect sizes were moderate in girls (~0.3 for adiposity and IR indicators), while, weaker values were found in boys. Serum 25(OH)D estimated cut-offs that best predicted total, central adiposity and IR were~30 ng ml
−1
. Children with suboptimal serum 25(OH)D (<30 ng ml
−1
) had a higher risk (two to three times) of being obese (high BAZ, body fat percent and/or central adiposity); and three to four times greater risk for IR.
Conclusions:
Serum 25(OH)D was inversely associated with adiposity (total and central) and IR indicators in prepubertal Chilean children. The conventional cut-off of vitamin D sufficiency (⩾30 ng ml
−1
) was adequate to assess obesity and IR risk in this age group.</description><subject>692/308/174</subject><subject>692/499</subject><subject>692/53</subject><subject>692/699/317</subject><subject>692/700/1720</subject><subject>82</subject><subject>82/51</subject><subject>Adiposity</subject><subject>Age</subject><subject>Analysis</subject><subject>Body Composition</subject><subject>Body fat</subject><subject>Body Mass Index</subject><subject>Care and treatment</subject><subject>Child</subject><subject>Children</subject><subject>Children & youth</subject><subject>Chile - epidemiology</subject><subject>Cohort analysis</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Food science</subject><subject>Health aspects</subject><subject>Health Promotion and Disease Prevention</subject><subject>Humans</subject><subject>Insulin Resistance</subject><subject>Internal Medicine</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metabolic Diseases</subject><subject>Metabolism</subject><subject>Nutrition</subject><subject>Obesity</subject><subject>Obesity, Abdominal - blood</subject><subject>Obesity, Abdominal - epidemiology</subject><subject>Obesity, Abdominal - etiology</subject><subject>original-article</subject><subject>Public Health</subject><subject>Standard scores</subject><subject>Vitamin D</subject><subject>Vitamin D - analogs & derivatives</subject><subject>Vitamin D - blood</subject><subject>Vitamin D Deficiency - blood</subject><subject>Vitamin D Deficiency - complications</subject><subject>Vitamin D Deficiency - epidemiology</subject><issn>0307-0565</issn><issn>1476-5497</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqNks1rFTEUxYMotlZ3riUgiAvnme_MLEv9qFBwYfdDJrnTl8dM8kwy1vffm9dXtZUuJIsLub9z4CQHoZeUrCjh7Xu_iStGqFxR0T5Cx1Ro1UjR6cfomHCiGyKVPELPct4QQqQk7Ck6YoopoaU-RtffIC0zZrI537kUf-5--GJmH_AHbHKO1psCDl_7ssY-OG9NiSnjOOIhuh0eTcEmuLrKy1RFCbLPxQQL9QpvE2yXAVIxE7ZrP4EJN9MlCM_Rk9FMGV7czhN0-enj5dl5c_H185ez04vGyk6VhjozOs2NcZwLOlCquo5L17pWaqWASTEIpQRlrQM9mmHsOks7a0FzNriRn6C3B9ttit8XyKWffbYwTSZAXHJPtZJdS6Wm_4FKQdquE21FX_-DbuKSQs2xpzhjilP9l7oyE_Q-jLEkY_em_akQ9S9arkilVg9Q9TiYvY0Bxvpw9wVv7gjWYKayznFaio8h3wffHUCbYs4Jxn6b_GzSrqek31enr9Xp99Xp6U2oV7ehlmEG9wf-3ZUKNAcg11W4gnQn9UOGvwD66svw</recordid><startdate>20160101</startdate><enddate>20160101</enddate><creator>Cediel, G</creator><creator>Corvalán, C</creator><creator>Aguirre, C</creator><creator>de Romaña, D L</creator><creator>Uauy, R</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T2</scope><scope>7TK</scope><scope>7TS</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>7U2</scope></search><sort><creationdate>20160101</creationdate><title>Serum 25-Hydroxyvitamin D associated with indicators of body fat and insulin resistance in prepubertal chilean children</title><author>Cediel, G ; Corvalán, C ; Aguirre, C ; de Romaña, D L ; Uauy, R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c596t-1dafd73aad3341b1169935d8d85766e254b4664128de7fabf99c19cce732bdf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>692/308/174</topic><topic>692/499</topic><topic>692/53</topic><topic>692/699/317</topic><topic>692/700/1720</topic><topic>82</topic><topic>82/51</topic><topic>Adiposity</topic><topic>Age</topic><topic>Analysis</topic><topic>Body Composition</topic><topic>Body fat</topic><topic>Body Mass Index</topic><topic>Care and treatment</topic><topic>Child</topic><topic>Children</topic><topic>Children & youth</topic><topic>Chile - epidemiology</topic><topic>Cohort analysis</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Food science</topic><topic>Health aspects</topic><topic>Health Promotion and Disease Prevention</topic><topic>Humans</topic><topic>Insulin Resistance</topic><topic>Internal Medicine</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metabolic Diseases</topic><topic>Metabolism</topic><topic>Nutrition</topic><topic>Obesity</topic><topic>Obesity, Abdominal - blood</topic><topic>Obesity, Abdominal - epidemiology</topic><topic>Obesity, Abdominal - etiology</topic><topic>original-article</topic><topic>Public Health</topic><topic>Standard scores</topic><topic>Vitamin D</topic><topic>Vitamin D - analogs & derivatives</topic><topic>Vitamin D - blood</topic><topic>Vitamin D Deficiency - blood</topic><topic>Vitamin D Deficiency - complications</topic><topic>Vitamin D Deficiency - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cediel, G</creatorcontrib><creatorcontrib>Corvalán, C</creatorcontrib><creatorcontrib>Aguirre, C</creatorcontrib><creatorcontrib>de Romaña, D L</creatorcontrib><creatorcontrib>Uauy, R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database (ProQuest Medical & Health Databases)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Agriculture Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Psychology Database</collection><collection>ProQuest Biological Science Journals</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Safety Science and Risk</collection><jtitle>International Journal of Obesity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cediel, G</au><au>Corvalán, C</au><au>Aguirre, C</au><au>de Romaña, D L</au><au>Uauy, R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Serum 25-Hydroxyvitamin D associated with indicators of body fat and insulin resistance in prepubertal chilean children</atitle><jtitle>International Journal of Obesity</jtitle><stitle>Int J Obes</stitle><addtitle>Int J Obes (Lond)</addtitle><date>2016-01-01</date><risdate>2016</risdate><volume>40</volume><issue>1</issue><spage>147</spage><epage>152</epage><pages>147-152</pages><issn>0307-0565</issn><eissn>1476-5497</eissn><abstract>Background:
Consistent data on the relation between vitamin D, body fat and insulin resistance (IR) in children are lacking.
Objectives:
(1) To evaluate the association between serum 25-Hydroxyvitamin D [25(OH)D] and key indicators of: adiposity (total and central), IR, and (2) to estimate serum 25(OH)D cut-offs that best reflect IR and total and central adiposity in children.
Subjects/Methods:
Prepubertal children (
n
=435, ~53% girls; ~age 7 years) from the Growth and Obesity Chilean Cohort Study were evaluated for potential associations between serum 25(OH)D and indicators of: (1) total adiposity (body mass index by age (BAZ), body fat (including three-component model)), central adiposity (waist circumference and trunk fatness); (2) IR (homeostasis model assessment of IR) and insulin sensitive (quantitative insulin sensitivity check index) using standardized multiple regression models with standardized coefficients and receiver operating characteristic curves.
Results:
Overall, mean serum 25(OH)D was 32.1±9.2 ng ml
−1
, while 19.4% of children were obese (BAZ⩾2 s.d.). Serum 25(OH)D was inversely associated with indicators of total and central adiposity and with IR indicators. Effect sizes were moderate in girls (~0.3 for adiposity and IR indicators), while, weaker values were found in boys. Serum 25(OH)D estimated cut-offs that best predicted total, central adiposity and IR were~30 ng ml
−1
. Children with suboptimal serum 25(OH)D (<30 ng ml
−1
) had a higher risk (two to three times) of being obese (high BAZ, body fat percent and/or central adiposity); and three to four times greater risk for IR.
Conclusions:
Serum 25(OH)D was inversely associated with adiposity (total and central) and IR indicators in prepubertal Chilean children. The conventional cut-off of vitamin D sufficiency (⩾30 ng ml
−1
) was adequate to assess obesity and IR risk in this age group.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>26264757</pmid><doi>10.1038/ijo.2015.148</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0307-0565 |
| ispartof | International Journal of Obesity, 2016-01, Vol.40 (1), p.147-152 |
| issn | 0307-0565 1476-5497 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1765981571 |
| source | Nature Publishing Group; Springer Link |
| subjects | 692/308/174 692/499 692/53 692/699/317 692/700/1720 82 82/51 Adiposity Age Analysis Body Composition Body fat Body Mass Index Care and treatment Child Children Children & youth Chile - epidemiology Cohort analysis Epidemiology Female Follow-Up Studies Food science Health aspects Health Promotion and Disease Prevention Humans Insulin Resistance Internal Medicine Longitudinal Studies Male Medicine Medicine & Public Health Metabolic Diseases Metabolism Nutrition Obesity Obesity, Abdominal - blood Obesity, Abdominal - epidemiology Obesity, Abdominal - etiology original-article Public Health Standard scores Vitamin D Vitamin D - analogs & derivatives Vitamin D - blood Vitamin D Deficiency - blood Vitamin D Deficiency - complications Vitamin D Deficiency - epidemiology |
| title | Serum 25-Hydroxyvitamin D associated with indicators of body fat and insulin resistance in prepubertal chilean children |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T05%3A34%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Serum%2025-Hydroxyvitamin%20D%20associated%20with%20indicators%20of%20body%20fat%20and%20insulin%20resistance%20in%20prepubertal%20chilean%20children&rft.jtitle=International%20Journal%20of%20Obesity&rft.au=Cediel,%20G&rft.date=2016-01-01&rft.volume=40&rft.issue=1&rft.spage=147&rft.epage=152&rft.pages=147-152&rft.issn=0307-0565&rft.eissn=1476-5497&rft_id=info:doi/10.1038/ijo.2015.148&rft_dat=%3Cgale_proqu%3EA440058360%3C/gale_proqu%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c596t-1dafd73aad3341b1169935d8d85766e254b4664128de7fabf99c19cce732bdf3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1753226317&rft_id=info:pmid/26264757&rft_galeid=A440058360&rfr_iscdi=true |