Maternal Psychiatric Disorder and the Risk of Autism Spectrum Disorder or Intellectual Disability in Subsequent Offspring

Psychiatric disorders are more common in the mothers of children with autism spectrum disorder (ASD) or intellectual disability (ID) after the birth of their child. We aimed to assess the relationship between women’s psychiatric contacts and subsequent offspring with ASD/ID. We linked three Western...

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Bibliographic Details
Published in:Journal of autism and developmental disorders 2016-02, Vol.46 (2), p.523-533
Main Authors: Fairthorne, Jenny, Hammond, Geoff, Bourke, Jenny, de Klerk, Nick, Leonard, Helen
Format: Article
Language:English
Subjects:
Adult
Australia
Autism
Autism Spectrum Disorder - genetics
Autism Spectrum Disorders
Autistic children
Behavioral Science and Psychology
Care and treatment
Child
Child and School Psychology
Child of Impaired Parents - psychology
Childbirth & labor
Children
Complications and side effects
Correlation
Departments
Disability
Discourse
Down Syndrome
Drug Therapy
Environmental Influences
Female
Females
Fetal Alcohol Syndrome
Foreign Countries
Genetic Predisposition to Disease - genetics
Genetics
Humans
Inheritance Patterns - genetics
Intellectual disabilities
Intellectual Disability
Intellectual Disability - genetics
Language Impairments
Learning disabilities
Mental Disorders
Mental Disorders - genetics
Mental Health
Mothers
Mothers - psychology
Neurosciences
Offspring
Original Paper
Parents
Patients
Pediatrics
Pervasive Developmental Disorders
Pregnancy
Prescribed
Psychiatric Services
Psychiatry
Psychology
Public Health
Registers
Risk
Risk factors
Women
Young Adult
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Description
Summary:Psychiatric disorders are more common in the mothers of children with autism spectrum disorder (ASD) or intellectual disability (ID) after the birth of their child. We aimed to assess the relationship between women’s psychiatric contacts and subsequent offspring with ASD/ID. We linked three Western Australian registers to investigate pre-existing maternal outpatient psychiatric contacts and the odds of ASD/ID in a subsequent child. Women with a previous outpatient psychiatric contact were more than twice as likely to have a child with ASD [OR 2.07 (95 % CI 1.7, 2.6)] or ID [OR 2.31 (2.1, 2.6)]. Further research exploring the effect on pregnancy outcomes of medications prescribed to women with psychiatric disorders is implicated.
ISSN:0162-3257
1573-3432
DOI:10.1007/s10803-015-2594-3