Unusual presentation of melanoma of unknown primary origin: A case report and review of literature

Malignant melanomas often present with metastasis to regional lymph nodes. Patients are also known to present with metastatic nodes in the absence of a known primary. However metastatic melanoma involving the stomach is rare in the scenario of an unknown primary lesion. We present a case of a 41-yea...

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Bibliographic Details
Published in:Journal of cancer research and therapeutics 2015-10, Vol.11 (4), p.1025-1025
Main Authors: Bankar, Sanket, Patkar, Shraddha, Desai, Sangeeta, Shrikhande, Shailesh V
Format: Article
Language:English
Subjects:
Adult
Biomarkers, Tumor - metabolism
Care and treatment
Complications and side effects
Female
Humans
Immunoenzyme Techniques
Melanoma
Melanoma - metabolism
Melanoma - pathology
Melanoma - surgery
Neoplasms, Unknown Primary - metabolism
Neoplasms, Unknown Primary - pathology
Neoplasms, Unknown Primary - surgery
Patient outcomes
Prognosis
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Summary:Malignant melanomas often present with metastasis to regional lymph nodes. Patients are also known to present with metastatic nodes in the absence of a known primary. However metastatic melanoma involving the stomach is rare in the scenario of an unknown primary lesion. We present a case of a 41-year-old lady who was treated for nodal disease in the right axilla 8. months earlier with an unknown primary. She later presented to us with a recurrent right axillary swelling and on evaluation was found to also have a nodular deposit on the greater curvature of the stomach. Histopathology of the deposit in conjunction with immunohistochemical markers S.100P, Melan-A and HMB-45, confirmed the diagnosis of malignant melanoma. The patient underwent surgical excision of both lesions and is now on regular follow-up.
ISSN:0973-1482
1998-4138
DOI:10.4103/0973-1482.148680