Direct ammonium fumarate production by Rhizopus arrhizus under phosphorous limitation

Direct ammonium fumarate production from glucose-based media with Rhizopus arrhizus NRRL 1526 was obtained using 2-kmol (NH^sub 4^)^sub 2^CO^sub 3^ per-m^sup 3^ as neutralising agent and controlling mycelial growth by phosphorous (P) limitation. As the P level in the production medium was increased...

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Bibliographic Details
Published in:Biotechnology letters 2000-07, Vol.22 (13), p.1043-1047
Main Authors: RISCALDATI, E, MORESI, M, FEDERICI, F, PETRUCCIOLI, M
Format: Article
Language:English
Subjects:
Ammonia
Ammonium
ammonium fumarate
Biological and medical sciences
Biotechnology
Fundamental and applied biological sciences. Psychology
Methods. Procedures. Technologies
Microbial engineering. Fermentation and microbial culture technology
Phosphorus content
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Summary:Direct ammonium fumarate production from glucose-based media with Rhizopus arrhizus NRRL 1526 was obtained using 2-kmol (NH^sub 4^)^sub 2^CO^sub 3^ per-m^sup 3^ as neutralising agent and controlling mycelial growth by phosphorous (P) limitation. As the P level in the production medium was increased from 0 to 0.3-kg of KH^sub 2^PO^sub 4^ per m^sup 3^, the fumarate yield decreased from 0.32 to 0.13-g per-g of glucose consumed; maximum ammonium fumarate productivity (0.46-kg-m^sup -3^-h^sup -1^) was obtained when using 0.1-kg phosphate-m^sup -3^.[PUBLICATION ABSTRACT]
ISSN:0141-5492
1573-6776
DOI:10.1023/A:1005621311898