Lamellar Macular Holes Associated with End-Stage Exudative Age-Related Macular Degeneration

Reports of lamellar macular holes (LMHs) with underlying age-related macular degeneration (AMD) are rare, and the specific definition, pathogenesis and surgical recommendations for this macular condition remain unclear. To present a series of LMHs in eyes with underlying end-stage AMD, and describe...

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Bibliographic Details
Published in:The Israel Medical Association journal 2015-12, Vol.17 (12), p.750-754
Main Authors: Segal, Ori, Ferencz, Joseph R, Mimouni, Michael, Nesher, Ronit, Cohen, Perri, Nemet, Arie Y
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Female
Follow-Up Studies
Humans
Macular Degeneration - physiopathology
Male
Middle Aged
Retinal Perforations - diagnosis
Retinal Perforations - etiology
Retinal Perforations - pathology
Retrospective Studies
Tomography, Optical Coherence - methods
Visual Acuity
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Summary:Reports of lamellar macular holes (LMHs) with underlying age-related macular degeneration (AMD) are rare, and the specific definition, pathogenesis and surgical recommendations for this macular condition remain unclear. To present a series of LMHs in eyes with underlying end-stage AMD, and describe optical coherence tomography (OCT) detection of associated morphologic abnormalities. We reviewed the files of consecutive patients diagnosed with LMH and underlying end-stage AMD between September 2007 and September 2011. Sixteen eyes of 14 patients were included in this study. The average follow-up after the OCT-established diagnosis of LMH was 19.8 months (range 4-48). The average visual acuity (VA) at last follow-up visit was 20/400 (20/60-20/1200). The best-corrected VA was stable in 10 eyes (62.5%) and deteriorated in 6 (37.5%). There was a statistically significant correlation between VA and minimal foveal thickness (r = -0.598, P = 0.014). In this series of LMHs with underlying AMD the OCT findings were intraretinal fluid, cystic spaces and window defect.
ISSN:1565-1088