Comparative study of inorganic elements determined in whole blood from Dmd(mdx)/J mice strain by EDXRF and NAA analytical techniques

Several diseases can be diagnosed observing the variation of specific elements concentration in body fluids. In this study the concentration of inorganic elements in blood samples of dystrophic (Dmd(mdx)/J) and C57BL/6J (control group) mice strain were determined. The results obtained from Energy Di...

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Bibliographic Details
Published in:Applied radiation and isotopes 2016-04, Vol.110, p.189-192
Main Authors: Redígolo, M M, Sato, I M, Metairon, S, Zamboni, C B
Format: Article
Language:English
Subjects:
Animals
Blood Chemical Analysis - methods
Disease Models, Animal
Elements
Female
Inorganic Chemicals - blood
Male
Mice
Mice, Inbred C57BL
Mice, Inbred mdx
Muscular Dystrophy, Duchenne - blood
Neutron Activation Analysis - methods
Spectrometry, X-Ray Emission - methods
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Summary:Several diseases can be diagnosed observing the variation of specific elements concentration in body fluids. In this study the concentration of inorganic elements in blood samples of dystrophic (Dmd(mdx)/J) and C57BL/6J (control group) mice strain were determined. The results obtained from Energy Dispersive X-ray Fluorescence (EDXRF) were compared with Neutron Activation Analysis (NAA) technique. Both analytical techniques showed to be appropriate and complementary offering a new contribution for veterinary medicine as well as detailed knowledge of this pathology.
ISSN:1872-9800
DOI:10.1016/j.apradiso.2016.01.022