Making Waves toward the Shore by Synchronicity

A study by Tsiairis and Aulehla (2016), published in Cell, reveals that randomized mixtures of dissociated presomitic mesoderm (PSM) cells reestablish wave-like propagating patterns of oscillatory gene expression by tuning the oscillation dynamics in response to surrounding cells. Thus, PSM cells se...

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Bibliographic Details
Published in:Developmental cell 2016-02, Vol.36 (4), p.358-359
Main Authors: Shimojo, Hiromi, Kageyama, Ryoichiro
Format: Article
Language:English
Subjects:
Animals
Biological Clocks
Embryo, Mammalian - metabolism
Gene Expression Regulation, Developmental
Mesoderm - metabolism
Organizers, Embryonic - metabolism
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Summary:A study by Tsiairis and Aulehla (2016), published in Cell, reveals that randomized mixtures of dissociated presomitic mesoderm (PSM) cells reestablish wave-like propagating patterns of oscillatory gene expression by tuning the oscillation dynamics in response to surrounding cells. Thus, PSM cells self-organize the phase-coupled oscillators. A study by Tsiairis and Aulehla (2016), published in Cell, reveals that randomized mixtures of dissociated presomitic mesoderm (PSM) cells reestablish wave-like propagating patterns of oscillatory gene expression by tuning the oscillation dynamics in response to surrounding cells. Thus, PSM cells self-organize the phase-coupled oscillators.
ISSN:1534-5807
1878-1551
DOI:10.1016/j.devcel.2016.02.003