A first reported case of clear cell carcinoma associated with delayed extrusion of midurethral tape

We present the first reported case of clear cell carcinoma associated with a midurethral tape (MUT), the possible hypotheses and the management pitfalls we encountered. We report a 58-year-old woman who presented with symptoms of urinary tract infection and acute retention of urine associated with v...

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Bibliographic Details
Published in:International Urogynecology Journal 2016-03, Vol.27 (3), p.377-380
Main Authors: Lin, Harvard Zhenjia, Wu, Fiona Meiwen, Low, Jeffrey Jen Hui, Venkateswaran, Kotamma, Ng, Roy Kwok Weng
Format: Article
Language:English
Subjects:
Adenocarcinoma, Clear Cell - etiology
Female
Gynecology
Humans
Medicine
Medicine & Public Health
Middle Aged
Special Contribution
Suburethral Slings - adverse effects
Urology
Vaginal Neoplasms - etiology
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Summary:We present the first reported case of clear cell carcinoma associated with a midurethral tape (MUT), the possible hypotheses and the management pitfalls we encountered. We report a 58-year-old woman who presented with symptoms of urinary tract infection and acute retention of urine associated with vaginal tape exposure 10 years after placement of an inside–out transobturator tape. She subsequently had a partial transobturator tape excision and a diagnostic cystoscopy, which revealed inflammatory changes within the urethra. Postoperatively, her symptoms persisted and the vaginal epithelium healed poorly. A biopsy of the friable tissue reported clear cell carcinoma. Imaging showed a locally invasive periurethral mass and bony and lymphatic metastases. This was treated with palliative radiation therapy. She was still receiving palliative care 5 months after the initial surgery.
ISSN:0937-3462
1433-3023
DOI:10.1007/s00192-015-2876-5