Triglyceride levels and risk of type 2 diabetes mellitus: a longitudinal large study

The relationship between triglyceridemia and diabetes mellitus remains unclear. This study evaluated the risk of diabetes and impaired fasting glucose associated with a wide range of triglyceride levels. A longitudinal retrospective study was carried out employing data from a screening center betwee...

Full description

Saved in:
Bibliographic Details
Published in:Journal of investigative medicine 2016-02, Vol.64 (2), p.383-387
Main Authors: Beshara, Amani, Cohen, Eytan, Goldberg, Elad, Lilos, Pearl, Garty, Moshe, Krause, Ilan
Format: Article
Language:English
Subjects:
Adult
Aged
Blood Glucose - metabolism
Diabetes
Diabetes Mellitus, Type 2 - blood
Fasting - blood
Female
Follow-Up Studies
Humans
Logistic Models
Longitudinal Studies
Male
Middle Aged
Risk Factors
Triglycerides
Triglycerides - blood
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The relationship between triglyceridemia and diabetes mellitus remains unclear. This study evaluated the risk of diabetes and impaired fasting glucose associated with a wide range of triglyceride levels. A longitudinal retrospective study was carried out employing data from a screening center between the years 2000 and 2012. Inclusion criteria were absence of diabetes at baseline and attendance at the center at least twice over a 5-year period. Participants were divided by fasting blood glucose level (normal/impaired) at the first visit. A total of 5085 participants were eligible for the study. Of the 4164 normoglycemic participants at baseline, 40 (0.96%) had diabetes and 998 (24%) had impaired fasting glucose by the end of the study. On stepwise logistic regression analysis, every 10 mg/dL increase in triglyceride level significantly increased the risk of diabetes by 4% and of impaired fasting glucose by 2% (p
ISSN:1081-5589
1708-8267
DOI:10.1136/jim-2015-000025