A Hollow Foldecture with Truncated Trigonal Bipyramid Shape from the Self-Assembly of an 11-Helical Foldamer

The creation of self‐assembling microscale architectures that possess new and useful physical properties remains a significant challenge. Herein we report that an 11‐helical foldamer self‐assembles in a controlled manner to form a series of 3D foldectures with unusual three‐fold symmetrical shapes t...

Full description

Saved in:
Bibliographic Details
Published in:Angewandte Chemie 2015-11, Vol.127 (45), p.13402-13405
Main Authors: Eom, Jae-Hoon, Gong, Jintaek, Kwon, Sunbum, Jeon, Aram, Jeong, Rokam, Driver, Russell W., Lee, Hee-Seung
Format: Article
Language:eng ; ger
Subjects:
Assembling
Biocompatibility
Chemistry
Containment
Containment vessels
Diffraction
Foldamere
Hohle Nanostrukturen
Molekulare Architekturen
Morphology
Physical properties
Powder
Proteins
Selbstorganisation
Self assembly
Symmetry
Three dimensional
Utilities
Vehicles
Wirt-Gast-Systeme
X-ray diffraction
X-rays
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The creation of self‐assembling microscale architectures that possess new and useful physical properties remains a significant challenge. Herein we report that an 11‐helical foldamer self‐assembles in a controlled manner to form a series of 3D foldectures with unusual three‐fold symmetrical shapes that are distinct from those generated from 12‐helical foldamers. The foldamer packing motif was revealed by powder X‐ray diffraction technique, and provides an important link between the molecular‐level symmetry and the microscale morphologies. The utility of foldectures with hollow interiors as robust and well‐defined supramolecular hosts was demonstrated for inorganic, organic, and even protein guests. This work will pave the way for the design of functional foldectures with greater 3D shape diversity and for the development of biocompatible delivery vehicles and containment vessels. Riesige molekulare Behältnisse: Durch Selbstorganisation eines 11‐helikalen Foldamers entstehen kristalline hohle Architekturen mit der Form einer trunkierten trigonalen Bipyramide, die als molekulare Wirtstrukturen wirken. Die Strukturen erinnern in dieser Hinsicht an biologische Mikrokompartimente.
ISSN:0044-8249
1521-3757
DOI:10.1002/ange.201504248