The in situ synthesis of Ag/amino acid biopolymer hydrogels as mouldable wound dressings

This manuscript introduces a one-pot fabrication procedure for the preparation of supramolecular hybrid hydrogels from low-cost commercially available natural products through a "green" strategy. In particular, the hybrid hydrogels, which are developed with Fmoc-Glu-OMe, silver nanoparticl...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2015-11, Vol.51 (87), p.15862-15865
Main Authors: Zhang, Zhenzhu, He, Ting, Yuan, Mengying, Shen, Rujuan, Deng, Liu, Yi, Lunzhao, Sun, Zhifang, Zhang, Yi
Format: Article
Language:English
Subjects:
Amino acids
Animals
Anti-Bacterial Agents - chemical synthesis
Anti-Bacterial Agents - pharmacology
Bandages, Hydrocolloid
Biomaterials
Biomedical materials
Chitosan - chemistry
Escherichia coli - drug effects
Fluorenes - chemistry
Glutamic Acid - analogs & derivatives
Glutamic Acid - chemistry
Green Chemistry Technology
Hydrogels
Male
Metal Nanoparticles - chemistry
Nanocomposites - chemistry
Nanoparticles
Particle Size
Rats
Rats, Sprague-Dawley
Silver
Silver Nitrate - chemistry
Strategy
Surgical implants
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Summary:This manuscript introduces a one-pot fabrication procedure for the preparation of supramolecular hybrid hydrogels from low-cost commercially available natural products through a "green" strategy. In particular, the hybrid hydrogels, which are developed with Fmoc-Glu-OMe, silver nanoparticles and chitosan, exhibit outstanding antibacterial properties and can be regarded as excellent mouldable wound healing biomaterials.
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc05195a