A stimuli-responsive and bioactive film based on blended polyvinyl alcohol and cashew gum polysaccharide

In this study, a stimuli-responsive, biodegradable and bioactive film was produced by blending cashew gum polysaccharide (CGP) and polyvinyl alcohol (PVA). The film presented malleability and mechanical properties enabling an easy handling. Wetting the film changed the optical property from opacity...

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Bibliographic Details
Published in:Materials Science & Engineering C 2016-01, Vol.58, p.927-934
Main Authors: Silva, Fábio E.F., Batista, Karla A., Di-Medeiros, Maria C.B., Silva, Cassio N.S., Moreira, Bruna R., Fernandes, Kátia F.
Format: Article
Language:English
Subjects:
Anacardium - metabolism
Biocompatibility
Biocompatible film
Biomedical materials
Cashew gum polysaccharide
Enzymes, Immobilized - chemistry
Enzymes, Immobilized - metabolism
Hydrogen-Ion Concentration
Materials science
Microscopy, Electron, Scanning
Papain
Papain - chemistry
Papain - metabolism
PEJU
pH stimuli-responsive
Polysaccharides
Polysaccharides - chemistry
Polysaccharides - isolation & purification
Polyvinyl Alcohol - chemistry
Polyvinyl alcohols
Proteolytic enzyme
Solvents
Spectroscopy, Fourier Transform Infrared
Wettability
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Summary:In this study, a stimuli-responsive, biodegradable and bioactive film was produced by blending cashew gum polysaccharide (CGP) and polyvinyl alcohol (PVA). The film presented malleability and mechanical properties enabling an easy handling. Wetting the film changed the optical property from opacity to levels of transparency higher than 70% and resulted in up to 2-fold increase in its superficial area. Different swelling indexes were obtained varying the pH of solvent, which allows classifying the CGP/PVA film as pH sensitive stimuli-responsive material. The bioactivity was achieved through covalent immobilization of papain, which remained active after storage of CGP/PVA-papain film for 24h in the presence of buffer or in a dry form. These results evidenced that CGP/PVA-papain film is a very promising material for biomedical applications. [Display omitted] •CGP/PVA film is a pH stimuli-responsive, biodegradable and biocompatible material.•CGP/PVA film is also a bioactive material after immobilization of papain.•CGP/PVA presented a short time for maximum swelling and high swelling index.•CGP/PVA film is a very promising material for biomedical applications.
ISSN:0928-4931
1873-0191
DOI:10.1016/j.msec.2015.09.064