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Inorganic hemostats: The state-of-the-art and recent advances
Hemorrhage is the most common cause of death both in hospitals and on the battlefield. The need for an effective hemostatic agent remains, since all injuries are not amenable to tourniquet use. There are many topical hemostatic agents and dressings available to control severe bleeding. This article...
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| Published in: | Materials Science & Engineering C 2016-01, Vol.58, p.1255-1268 |
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| Main Authors: | , , , , |
| Format: | Article |
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| cites | cdi_FETCH-LOGICAL-c455t-5b5a99d5d9cb07d5693b71a7b555c04f9e4e14246b2063aad977ab9af4ecdf663 |
| container_end_page | 1268 |
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| container_title | Materials Science & Engineering C |
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| creator | Pourshahrestani, Sara Zeimaran, Ehsan Djordjevic, Ivan Kadri, Nahrizul Adib Towler, Mark R. |
| description | Hemorrhage is the most common cause of death both in hospitals and on the battlefield. The need for an effective hemostatic agent remains, since all injuries are not amenable to tourniquet use. There are many topical hemostatic agents and dressings available to control severe bleeding. This article reviews the most commonly used inorganic hemostats, subcategorized as zeolite and clay-based hemostats. Their hemostatic functions as well as their structural properties that are believed to induce hemostasis are discussed. The most important findings from in vitro and in vivo experiments are also covered.
•A review of hemostatic function of inorganic hemostats including zeolite and clay-based materials•The mechanism of action of the hemostats is discussed.•Clay based materials have been shown to be more efficient for stoppage of blood flow compared to zeolite based hemostats.•Future methods of improving the hemostatic efficacy of hemostats are postulated. |
| doi_str_mv | 10.1016/j.msec.2015.09.008 |
| format | article |
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| language | eng |
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| source | ScienceDirect Freedom Collection |
| subjects | Animals Bandages Biomedical materials Disease Models, Animal Hemorrhage Hemorrhage - therapy Hemostasis Hemostatics Hospitals Humans In vitro testing Injuries Inorganic hemostat Kaolin Materials science Silicates Smectite State of the art Surgical implants Zeolite |
| title | Inorganic hemostats: The state-of-the-art and recent advances |
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