Association between C-reactive protein and physical performance in older populations: results from the International Mobility in Aging Study (IMIAS)

C-reactive protein (CRP) is a widely used cardiovascular risk marker, but questions remain about its role in the disability process in old age. This study examines the associations between CRP levels and physical performance in old age in different societies. data were collected during the baseline...

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Bibliographic Details
Published in:Age and ageing 2016-03, Vol.45 (2), p.274-280
Main Authors: Sousa, Ana Carolina Patrício Albuquerque, Zunzunegui, Maria-Victoria, Li, Annie, Phillips, Susan P, Guralnik, Jack M, Guerra, Ricardo Oliveira
Format: Article
Language:English
Subjects:
Adjustment
Age differences
Age Factors
Aged
Ageing
Aging
Aging - blood
Associations
Biomarkers
Biomarkers - blood
Blood pressure
Brazil
C-reactive protein
C-Reactive Protein - analysis
Canada
Cardiovascular diseases
Care and treatment
Chi-Square Distribution
Colombia
Cross-Sectional Studies
Data processing
Disability
Disability Evaluation
Elderly
Elderly people
Female
Formulae
Gait
Geriatric Assessment
Geriatrics
Grip strength
Hand
Hand Strength
Health aspects
Health behaviour
Health Status
Health Surveys
Human performance
Humans
Inflammation
Inflammation Mediators - blood
International mobility
Kinematics
Linear Models
Logistic Models
Male
Mobility
Multivariate Analysis
Odds Ratio
Older people
Physical ability
Physical Fitness
Proteins
Regression analysis
Risk Factors
Sensitivity
Socio-economic aspects
Socioeconomic factors
Statistical analysis
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Description
Summary:C-reactive protein (CRP) is a widely used cardiovascular risk marker, but questions remain about its role in the disability process in old age. This study examines the associations between CRP levels and physical performance in old age in different societies. data were collected during the baseline survey of IMIAS in 2012 in Kingston (Canada), Saint-Hyacinthe (Canada), Manizales (Colombia) and Natal (Brazil). Approximately 200 men and 200 women aged 65-74 were recruited at each site. CRP was assessed using a high sensitivity assay and categorised as low (
ISSN:0002-0729
1468-2834
DOI:10.1093/ageing/afv202