Evidence-based recommendations of postoperative radiotherapy in lung cancer from Oncologic Group for the Study of Lung Cancer (Spanish Radiation Oncology Society)

Locally advanced non-small cell lung cancer (NSCLC) is a diversified illness in which postoperative radiation therapy (PORT) for complete resection with positive hiliar (pN1) and/or mediastinal (pN2) lymph nodes is controversial. Although several studies have shown that PORT has beneficial effects,...

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Bibliographic Details
Published in:Clinical & translational oncology 2016-04, Vol.18 (4), p.331-341
Main Authors: Gómez, A., González, J. A., Couñago, F., Vallejo, C., Casas, F., de Dios, N. Rodríguez
Format: Article
Language:English
Subjects:
Humans
Lung Neoplasms - radiotherapy
Lung Neoplasms - surgery
Medicine
Medicine & Public Health
Oncology
Postoperative Period
Practice Guidelines as Topic - standards
Radiotherapy
Review Article
Societies, Medical
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Summary:Locally advanced non-small cell lung cancer (NSCLC) is a diversified illness in which postoperative radiation therapy (PORT) for complete resection with positive hiliar (pN1) and/or mediastinal (pN2) lymph nodes is controversial. Although several studies have shown that PORT has beneficial effects, randomized trials are needed to demonstrate its impact on overall survival. In this review, the Spanish Radiation Oncology Group for Lung Cancer describes the most relevant literature on PORT in NSCLC patients stage pN1–2. In addition, we have outlined the current recommendations of different national and international clinical guidelines and have also specified practical issues regarding treatment volume definition, doses and fractionation.
ISSN:1699-048X
1699-3055
DOI:10.1007/s12094-015-1374-z