Brain injury after induction chemotherapy in children with acute lymphoblastic leukemia

To investigate the changes in brain injury after the induction chemotherapy in children with acute lymphoblastic leukemia (ALL) by cranial MRI. The clinical data and cranial MRI results of 62 children with ALL who were hospitalized from March 2014 to June 2015 were analyzed retrospectively. Before c...

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Bibliographic Details
Published in:Zhongguo dang dai er ke za zhi 2016-03, Vol.18 (3), p.254
Main Authors: Zou, Dong-Fang, Zeng, Hong-Wu, Yu, Jie, Mai, Hui-Rong, Yuan, Xiu-Li, Wang, Li-Hong, Liao, Jian-Xiang, Wen, Fei-Qiu
Format: Article
Language:Chinese
Subjects:
Adolescent
Bone Marrow - pathology
Brain - drug effects
Brain - pathology
Child
Child, Preschool
Female
Humans
Induction Chemotherapy - adverse effects
Infant
Magnetic Resonance Imaging
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology
Retrospective Studies
Skull - pathology
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Summary:To investigate the changes in brain injury after the induction chemotherapy in children with acute lymphoblastic leukemia (ALL) by cranial MRI. The clinical data and cranial MRI results of 62 children with ALL who were hospitalized from March 2014 to June 2015 were analyzed retrospectively. Before chemotherapy, MRI showed bone marrow infiltration of the skull in 33 patients (53%); the children with WBC
ISSN:1008-8830
DOI:10.7499/j.issn.1008-8830.2016.03.013