Characterization and use of (E)-2-[(6-methoxybenzo[d]thiazol-2-ylimino)methyl]phenol as an anion sensor and a DNA-binding agent

[Display omitted] We report the spectroscopic characterization, DNA binding, and anion sensor properties, of a Schiff base, that is, (E)-2-[(6-methoxybenzo[d]thiazol-2-ylimino)methyl]phenol from the reaction of 2-hydroxybenzaldehyde with 2-amino-6-methoxybenzothiazole. Colorimetric measurements reve...

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Bibliographic Details
Published in:Tetrahedron letters 2016-02, Vol.57 (5), p.537-542
Main Authors: Barare, Belygona, Yıldız, Mustafa, Ünver, Hüseyin, Aslan, Kadir
Format: Article
Language:English
Subjects:
1H NMR titration
2-Amino-6-methoxybenzothiazole
Anion sensors
Calf thymus-DNA
Schiff base
Spectroscopy
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Summary:[Display omitted] We report the spectroscopic characterization, DNA binding, and anion sensor properties, of a Schiff base, that is, (E)-2-[(6-methoxybenzo[d]thiazol-2-ylimino)methyl]phenol from the reaction of 2-hydroxybenzaldehyde with 2-amino-6-methoxybenzothiazole. Colorimetric measurements revealed that the title compound was sensitive to F−, AcO−, CN−, and OH− anions. Fluorescence measurements demonstrated that the title compound can be used to detect CN−. The interactions between the receptor and anions were confirmed using 1H NMR titration method. The UV–Vis spectroscopy studies of the interactions between the compound and calf thymus DNA (CT-DNA) revealed intercalative binding of CT-DNA to the title compound.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2015.12.071