Impact of institutional culture on rates of transfusions during cardiovascular procedures: The Michigan experience

• Published in: The American heart journal 2016-04, Vol.174, p.1-6
• Main Authors: Likosky, Donald S., PhD, Zhang, Min, PhD, Paone, Gaetano, MD, MHSA, Collins, John, MD, DeLucia, Alphonse, MD, Schreiber, Theodore, MD, Theurer, Patty, BSN, RN, Kazziha, Samer, MD, Leffler, Dale, DO, Wunderly, Douglas J., MD, Gurm, Hitinder S., MD, Prager, Richard L., MD
• Format: Article
• Language: English
• Subjects: Aged; Body mass index; Cardiology; Cardiovascular; Cardiovascular disease; Coronary Artery Bypass; Coronary Artery Disease - surgery; Coronary vessels; Erythrocyte Transfusion - utilization; Family medical history; Female; Follow-Up Studies; Guideline Adherence; Heart attacks; Heart failure; Humans; Intraoperative Care - methods; Lung diseases; Male; Michigan - epidemiology; Middle Aged; Morbidity - trends; Mortality; Percutaneous Coronary Intervention; Postoperative Complications - epidemiology; Postoperative Complications - prevention & control; Prognosis; Quality; Retrospective Studies; Review boards; Risk Assessment - methods; Studies; Surgery; Survival Rate - trends
• ISSN: 0002-8703; 1097-6744
• DOI: 10.1016/j.ahj.2015.12.019

Background Red blood cell (RBC) transfusions have been associated with morbidity and mortality in both coronary artery bypass grafting (CABG) and percutaneous coronary interventions (PCI). As a mechanism for identifying determinants of RBC practice, we quantified the relationship between a center's PCI and CABG transfusion rate. Methods We identified all patients undergoing CABG (n = 16,568) or PCI (n = 94,634) at each of 33 centers from 2010 through 2012 in the state of Michigan and compared perioperative RBC transfusion rates for CABG and PCI at each center. Crude and adjusted transfusion rates were modeled separately. We adjusted for common preprocedural risk factors (12 for CABG and 23 for PCI) and reported Pearson correlation coefficients based on the crude and risk-adjusted rates. Results As expected, RBC transfusion was more common after CABG (mean 46.5%) than PCI (mean 3.3%), with wide variation across centers for both (CABG min:max 26.5:71.3, PCI min:max 1.6:6.0). However, RBC transfusion rates were significantly correlated between CABG and PCI in both crude, 0.48 ( P = .005), and adjusted, 0.53 ( P = .001), analyses. These findings were consistent when restricting to nonemergent cases ( radj = 0.44, P = .001). Conclusions Red blood cell transfusion rates were significantly correlated between the CABG and PCI at individual hospitals in Michigan, independent of patient case mix. Future work should explore institutional practice patterns, philosophies, and guidelines for RBC transfusions.