Extrahepatic manifestations of hepatitis E virus

Hepatitis E virus can cause acute, fulminant and chronic hepatitis and has been associated with a range of extrahepatic manifestations. Guillain–Barré syndrome, neuralgic amyotrophy and encephalitis are the main neurological manifestations associated with acute and chronic hepatitis E virus infectio...

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Bibliographic Details
Published in:Liver international 2016-04, Vol.36 (4), p.467-472
Main Authors: Kamar, Nassim, Marion, Olivier, Abravanel, Florence, Izopet, Jacques, Dalton, Harry R.
Format: Article
Language:English
Subjects:
Acute Disease
Anaemia
Anemia - diagnosis
Anemia - virology
Animals
Cryoglobulinemia - diagnosis
Cryoglobulinemia - virology
Guillain-Barré syndrome
Hepatitis E - complications
Hepatitis E - diagnosis
Hepatitis E - virology
hepatitis E virus
Hepatitis E virus - pathogenicity
Host-Pathogen Interactions
Humans
kidney disease
Kidney Diseases - diagnosis
Kidney Diseases - virology
Nervous System Diseases - diagnosis
Nervous System Diseases - virology
neuralgic amyotrophy
pancreatitis
Pancreatitis - diagnosis
Pancreatitis - virology
Risk Factors
thrombocytopenia
Thrombocytopenia - diagnosis
Thrombocytopenia - virology
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Summary:Hepatitis E virus can cause acute, fulminant and chronic hepatitis and has been associated with a range of extrahepatic manifestations. Guillain–Barré syndrome, neuralgic amyotrophy and encephalitis are the main neurological manifestations associated with acute and chronic hepatitis E virus infection. Renal injuries have been also reported, including membranoproliferative glomerulonephritis with or without cryoglobulinemia and membranous glomerulonephritis. Acute pancreatitis, haematological disorders and other autoimmune extrahepatic manifestations of hepatitis E virus, such as myocarditis and thyroiditis, have been also reported. In this comprehensive article, we review all published reports describing hepatitis E virus–associated extrahepatic manifestations.
ISSN:1478-3223
1478-3231
DOI:10.1111/liv.13037