Early Antibiotic Treatment May Prevent Complete Development of Lemierre's Syndrome: Experience from 2 Cases

Lemierre's syndrome is a rare fulminant condition caused by an acute oropharyngeal infection, with secondary septic thrombophlebitis of the internal jugular vein complicated by multiple metastatic infections. Herein we report 2 patients with internal jugular vein thrombosis secondary to orophar...

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Bibliographic Details
Published in:Scandinavian journal of infectious diseases 2000, Vol.32 (6), p.706-707
Main Author: Yaniv Sherer, Joseph Mishal, Octavian Leibovici
Format: Article
Language:English
Subjects:
Adult
Amoxicillin-Potassium Clavulanate Combination - therapeutic use
Anti-Bacterial Agents - therapeutic use
Bacterial diseases
Biological and medical sciences
Clindamycin - therapeutic use
Drug Therapy, Combination - therapeutic use
Ent and stomatologic bacterial diseases
Fusobacterium necrophorum
Human bacterial diseases
Humans
Infectious diseases
Jugular Veins
Lemierre's syndrome
Male
Medical sciences
Pharyngitis - complications
Pharyngitis - drug therapy
Syndrome
Thrombophlebitis - complications
Thrombophlebitis - diagnosis
Thrombophlebitis - drug therapy
Tonsillitis - complications
Tonsillitis - diagnosis
Tonsillitis - drug therapy
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Summary:Lemierre's syndrome is a rare fulminant condition caused by an acute oropharyngeal infection, with secondary septic thrombophlebitis of the internal jugular vein complicated by multiple metastatic infections. Herein we report 2 patients with internal jugular vein thrombosis secondary to oropharyngeal infection, whose clinical course was indolent, and who were asymptomatic shortly after antibiotic therapy was begun. Careful examination of the neck in patients presenting with sore throat could help identify the typical 'cord sign'. In such cases, intravenous antibiotic treatment should be started as soon as possible to prevent development of metastatic infections and septicaemia characterizing Lemierre's syndrome.
ISSN:0036-5548
1651-1980
DOI:10.1080/003655400459711