Dark Blood Magnetic Resonance Lymphangiography Using Dual-Agent Relaxivity Contrast (DARC-MRL): A Novel Method Combining Gadolinium and Iron Contrast Agents

The objective of this study was to develop and demonstrate a technique to eliminate venous enhancement in contrast-enhanced magnetic resonance lymphangiography through shortening T2⁎ in the blood pool, thus allowing for a lymphatic-only map. Administration of the blood-pool iron agent ferumoxtyol in...

Full description

Saved in:
Bibliographic Details
Published in:Current problems in diagnostic radiology 2016-05, Vol.45 (3), p.174-179
Main Authors: Maki, Jeffrey H., MD, PhD, Neligan, Peter C., MD, Briller, Noah, RT (R)(MR), Mitsumori, Lee M., MD, Wilson, Gregory J., PhD
Format: Article
Language:English
Subjects:
Blood - diagnostic imaging
Contrast Media
Ferrosoferric Oxide
Gadolinium DTPA
Humans
Image Enhancement - methods
Internal Medicine
Lymphedema - diagnostic imaging
Lymphography - methods
Magnetic Resonance Imaging - methods
Phantoms, Imaging
Radiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The objective of this study was to develop and demonstrate a technique to eliminate venous enhancement in contrast-enhanced magnetic resonance lymphangiography through shortening T2⁎ in the blood pool, thus allowing for a lymphatic-only map. Administration of the blood-pool iron agent ferumoxtyol in addition to intracutaneous gadolinium during contrast-enhanced magnetic resonance lymphangiography allows for suppression of vascular structures to achieve venous-free lymphatic mapping.
ISSN:0363-0188
1535-6302
DOI:10.1067/j.cpradiol.2015.08.003