Helicobacter pylori Infection Rates in Patients Undergoing Endoscopy in the Interior of Borneo

• Published in: Helicobacter (Cambridge, Mass.) Mass.), 2016-04, Vol.21 (2), p.158-162
• Main Authors: Chai, Feng Yih, Chong, Hock Chin, Tan, Yew Eng, Heng, Sophia Si Ling, Asilah, Siti Mohd Desa, Ridwan, Hashim
• Format: Article
• Language: English
• Subjects: Adult; Aged; Borneo; Borneo - epidemiology; Endoscopy; Endoscopy, Gastrointestinal; epidemiology; Female; Health risk assessment; Helicobacter Infections - epidemiology; Helicobacter pylori; Helicobacter pylori - isolation & purification; Humans; Infections; Malaysia; Male; Middle Aged; Retrospective Studies; Risk Factors; Sabah; Ulcers; Urease - analysis
• ISSN: 1083-4389; 1523-5378
• DOI: 10.1111/hel.12264

Introduction Very limited data are available on the Helicobacter pylori infection among the population of interior Borneo. We aimed to investigate the H. pylori infection rate among an endoscoped interior Borneo population and to report the differences between the infected and noninfected patients. Methods We retrospectively analyzed the data of the rapid urease test (RUT) records in Endoscopy Unit Hospital Keningau from January 2009 to May 2014. Student's t‐test, chi‐square test or Fisher's exact test were used accordingly. Multiple logistic regression analysis was used to identify independent risk factors for H. pylori infection. Birth cohort was analyzed against H. pylori infection rate with chi‐square test. Results Overall, there were 215 of 774 (27.8%) positive RUTs. Patients with H. pylori infection were younger (47.66 ± 14.93 vs 50.50 ± 15.02 years, p = .019), more likely to be female (OR = 1.54, 95% CI 1.12–2.13, p = .008) and originated from the Pensiangan district (OR = 1.63, 95% CI 1.01–2.64, p = .047). Chinese patients were less likely infected with H. pylori (OR = 0.36, 95% CI 0.16–0.80, p = .013). Birth cohort was significantly associated with H. pylori infection rate (χ2(7) = 14.71, p = .040) with an increasing trend of H. pylori infection rate in patients born later (χ2(1) = 5.26, p = .022). Conclusion The overall H. pylori infection rate in this population was unexpectedly low. Accordingly, it may be a recent arrival in this community. Gender, age, dietary practice, socioeconomic status, and ethnicity were among the factors associated with H. pylori infection.