Regional body fat depots differently affect bone microarchitecture in postmenopausal Korean women

Summary In a prospective community-based cohort study, we investigated the relationship between trabecular bone score (TBS) and regional fat depots in 1474 Korean postmenopausal women. TBS was positively related with subcutaneous fat and negatively related with visceral fat. Introduction The effect...

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Bibliographic Details
Published in:Osteoporosis international 2016-03, Vol.27 (3), p.1161-1168
Main Authors: Kim, J. H., Choi, H. J., Ku, E. J., Hong, A. R., Kim, K. M., Kim, S. W., Cho, N. H., Shin, C. S.
Format: Article
Language:English
Subjects:
Absorptiometry, Photon - methods
Adipose Tissue - anatomy & histology
Adult
Aged
Anthropometry - methods
Body Composition - physiology
Body fat
Body Fat Distribution
Bone Density - physiology
Bones
Cancellous Bone - diagnostic imaging
Cross-Sectional Studies
Endocrinology
Female
Hip Joint - diagnostic imaging
Hip Joint - physiology
Humans
Intra-Abdominal Fat - anatomy & histology
Lumbar Vertebrae - diagnostic imaging
Lumbar Vertebrae - physiology
Medicine
Medicine & Public Health
Menopause
Middle Aged
Original Article
Orthopedics
Postmenopause - physiology
Rheumatology
Subcutaneous Fat - anatomy & histology
Women
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Summary:Summary In a prospective community-based cohort study, we investigated the relationship between trabecular bone score (TBS) and regional fat depots in 1474 Korean postmenopausal women. TBS was positively related with subcutaneous fat and negatively related with visceral fat. Introduction The effect of fat distribution (visceral/subcutaneous) on bone quality or microarchitecture has rarely been investigated due to measurement difficulty. We aimed to investigate the relationship between TBS reflecting bone microarchitecture and regional fat depots in Korean women. Methods Cross-sectional data evaluation was made from subjects participating in an ongoing prospective community-based cohort study since 2001. A total of 1474 postmenopausal women in the Ansung cohort were analyzed. Regional body fat mass, bone mineral density (BMD) at the lumbar spine, and total hip and lumbar spine TBS were measured by dual energy X-ray absorptiometry (DXA). Results In an age-adjusted partial correlation analysis, TBS was not associated with total fat mass, but negatively associated with trunk fat mass. However, TBS was positively related with leg ( r  = 0.102, P  
ISSN:0937-941X
1433-2965
DOI:10.1007/s00198-015-3329-1