Frequencies of chromosome aberrations in a control population determined by G banding

Control data on chromosome aberration frequencies determined by G banding from several studies undertaken in this laboratory have been re-analysed in relation to age and smoking. The combined study group comprised a total of 162 men (90 non-smokers and 72 smokers) with ages ranging from 20 to 72 yea...

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Bibliographic Details
Published in:Mutation research. Genetic toxicology and environmental mutagenesis 2001-02, Vol.490 (2), p.171-177
Main Authors: Tawn, E.Janet, Whitehouse, Caroline A.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Chromosome aberrations
Control populations
Drug toxicity and drugs side effects treatment
G banding
Medical sciences
Miscellaneous (drug allergy, mutagens, teratogens...)
Pharmacology. Drug treatments
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Summary:Control data on chromosome aberration frequencies determined by G banding from several studies undertaken in this laboratory have been re-analysed in relation to age and smoking. The combined study group comprised a total of 162 men (90 non-smokers and 72 smokers) with ages ranging from 20 to 72 years. For the group as a whole, significant increases were observed in translocations and all symmetrical exchanges with increasing age and also when smokers were compared with non-smokers.
ISSN:1383-5718
1879-3592
DOI:10.1016/S1383-5718(00)00164-9