Multiple lineages of the non-LTR retrotransposon Rex1 with varying success in invading fish genomes

Rex1, together with the related BABAR: elements, represents a new family of non-long-terminal-repeat (non-LTR) retrotransposons from fish, which might be related to the CR1 clade of LINE elements. Rex1/BABAR: retrotransposons encode a reverse transcriptase and an apurinic/apyrimidinic endonuclease,...

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Bibliographic Details
Published in:Molecular biology and evolution 2000-11, Vol.17 (11), p.1673-1684
Main Authors: Volff, J N, Körting, C, Schartl, M
Format: Article
Language:English
Subjects:
Acanthopterygii
Amino Acid Sequence
Anguilla japonica
Animals
Base Sequence
Danio rerio
DNA - chemistry
DNA - genetics
Esox lucius
Evolution, Molecular
Fishes - genetics
Fugu rubripes
Genome
Molecular Sequence Data
Phylogeny
Pisces
Poeciliidae
Retroelements - genetics
Sequence Alignment
Sequence Analysis, DNA
Sequence Homology, Amino Acid
Sequence Homology, Nucleic Acid
Time Factors
transposon Babar
transposon Rex1
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Summary:Rex1, together with the related BABAR: elements, represents a new family of non-long-terminal-repeat (non-LTR) retrotransposons from fish, which might be related to the CR1 clade of LINE elements. Rex1/BABAR: retrotransposons encode a reverse transcriptase and an apurinic/apyrimidinic endonuclease, which is very frequently removed by incomplete reverse transcription. Different Rex1 elements show a conserved terminal 3' untranslated region followed by oligonucleotide tandem repeats of variable size and sequence. Phylogenetic analysis revealed that Rex1 retrotransposons were frequently active during fish evolution. They formed multiple ancient lineages, which underwent several independent and recent bursts of retrotransposition and invaded fish genomes with varying success (from
ISSN:0737-4038
1537-1719
DOI:10.1093/oxfordjournals.molbev.a026266