Curcumin-reduced graphene oxide sheets and their effects on human breast cancer cells

Curcumin (as a natural reductant material) was utilized for green reduction and functionalization of chemically exfoliated graphene oxide (GO) sheets. The π–π attachment of the curcumin molecules onto the curcumin-reduced graphene oxide (rGO) sheets was confirmed by Raman and Fourier transform infra...

Full description

Saved in:
Bibliographic Details
Published in:Materials Science & Engineering C 2015-10, Vol.55, p.482-489
Main Authors: Hatamie, Shadie, Akhavan, Omid, Sadrnezhaad, Sayed Khatiboleslam, Ahadian, Mohammad Mahdi, Shirolkar, Mandar M., Wang, Haiqian Q.
Format: Article
Language:English
Subjects:
Biotechnology
Breast
Breast Neoplasms - pathology
Cancer
Cancer cells
Cell Line, Tumor
Cell viability
Curcumin
Curcumin - chemistry
Female
Graphene
Graphite - chemistry
Human
Humans
Oxides
Oxides - chemistry
Reduction
Spectrum Analysis
Toxicity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Curcumin (as a natural reductant material) was utilized for green reduction and functionalization of chemically exfoliated graphene oxide (GO) sheets. The π–π attachment of the curcumin molecules onto the curcumin-reduced graphene oxide (rGO) sheets was confirmed by Raman and Fourier transform infrared spectroscopies. Zeta potential of the GO sheets decreased from about −40mV to −20mV, after the green reduction and functionalization. The probable cytotoxicity of the curcumin-rGO sheets was studied through their interactions with two human breast cancer cell lines (MDA-MB-231 and SKBR3 cell lines) and a normal cell line (mouse fibroblast L929 cell line). The curcumin-rGO sheet with concentrations
ISSN:0928-4931
1873-0191
DOI:10.1016/j.msec.2015.05.077