Multiscale engineered hierarchical structures with precisely controlled sizes for bio-inspired cell culture

We present a simple method of fabricating bio-inspired multiscale structure by combining replica molding and surface wrinkling. With this technique, we demonstrates that our fabrication method is manageable to fabricate various types of substrate with various orientations of nanopatterns on microwri...

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Bibliographic Details
Published in:Materials letters 2015-11, Vol.159, p.213-217
Main Authors: Bae, Won-Gyu, Eui Jeong, Hoon, Kim, Jangho
Format: Article
Language:English
Subjects:
Biotechnology
Nanostructure
Orientation
Wrinkling
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Summary:We present a simple method of fabricating bio-inspired multiscale structure by combining replica molding and surface wrinkling. With this technique, we demonstrates that our fabrication method is manageable to fabricate various types of substrate with various orientations of nanopatterns on microwrinkle structure, resulting perfectly conform the wrinkling phenomenon. Finally we have explored cells behavior on multiscale substrate.
ISSN:0167-577X
DOI:10.1016/j.matlet.2015.06.122