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Clinical feasibility of a myocardial signal intensity threshold-based semi-automated cardiac magnetic resonance segmentation method

Objectives To assess the accuracy and efficiency of a threshold-based, semi-automated cardiac MRI segmentation algorithm in comparison with conventional contour-based segmentation and aortic flow measurements. Methods Short-axis cine images of 148 patients (55 ± 18 years, 81 men) were used to evalua...

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Published in:European radiology 2016-05, Vol.26 (5), p.1503-1511
Main Authors: Varga-Szemes, Akos, Muscogiuri, Giuseppe, Schoepf, U. Joseph, Wichmann, Julian L., Suranyi, Pal, De Cecco, Carlo N., Cannaò, Paola M., Renker, Matthias, Mangold, Stefanie, Fox, Mary A., Ruzsics, Balazs
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creator Varga-Szemes, Akos
Muscogiuri, Giuseppe
Schoepf, U. Joseph
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Renker, Matthias
Mangold, Stefanie
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description Objectives To assess the accuracy and efficiency of a threshold-based, semi-automated cardiac MRI segmentation algorithm in comparison with conventional contour-based segmentation and aortic flow measurements. Methods Short-axis cine images of 148 patients (55 ± 18 years, 81 men) were used to evaluate left ventricular (LV) volumes and mass (LVM) using conventional and threshold-based segmentations. Phase-contrast images were used to independently measure stroke volume (SV). LV parameters were evaluated by two independent readers. Results Evaluation times using the conventional and threshold-based methods were 8.4 ± 1.9 and 4.2 ± 1.3 min, respectively ( P   0.05) but were significantly different from conventional analysis ( P  
doi_str_mv 10.1007/s00330-015-3952-4
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Joseph ; Wichmann, Julian L. ; Suranyi, Pal ; De Cecco, Carlo N. ; Cannaò, Paola M. ; Renker, Matthias ; Mangold, Stefanie ; Fox, Mary A. ; Ruzsics, Balazs</creator><creatorcontrib>Varga-Szemes, Akos ; Muscogiuri, Giuseppe ; Schoepf, U. Joseph ; Wichmann, Julian L. ; Suranyi, Pal ; De Cecco, Carlo N. ; Cannaò, Paola M. ; Renker, Matthias ; Mangold, Stefanie ; Fox, Mary A. ; Ruzsics, Balazs</creatorcontrib><description>Objectives To assess the accuracy and efficiency of a threshold-based, semi-automated cardiac MRI segmentation algorithm in comparison with conventional contour-based segmentation and aortic flow measurements. Methods Short-axis cine images of 148 patients (55 ± 18 years, 81 men) were used to evaluate left ventricular (LV) volumes and mass (LVM) using conventional and threshold-based segmentations. Phase-contrast images were used to independently measure stroke volume (SV). LV parameters were evaluated by two independent readers. Results Evaluation times using the conventional and threshold-based methods were 8.4 ± 1.9 and 4.2 ± 1.3 min, respectively ( P  &lt; 0.0001). LV parameters measured by the conventional and threshold-based methods, respectively, were end-diastolic volume (EDV) 146 ± 59 and 134 ± 53 ml; end-systolic volume (ESV) 64 ± 47 and 59 ± 46 ml; SV 82 ± 29 and 74 ± 28 ml (flow-based 74 ± 30 ml); ejection fraction (EF) 59 ± 16 and 58 ± 17 %; and LVM 141 ± 55 and 159 ± 58 g. Significant differences between the conventional and threshold-based methods were observed in EDV, ESV, and LVM mesurements; SV from threshold-based and flow-based measurements were in agreement ( P  &gt; 0.05) but were significantly different from conventional analysis ( P  &lt; 0.05). Excellent inter-observer agreement was observed. Conclusions Threshold-based LV segmentation provides improved accuracy and faster assessment compared to conventional contour-based methods. Key Points • Threshold-based left ventricular segmentation provides time-efficient assessment of left ventricular parameters • The threshold-based method can discriminate between blood and papillary muscles • This method provides improved accuracy compared to aortic flow measurements as a reference</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-015-3952-4</identifier><identifier>PMID: 26267520</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Accuracy ; Algorithms ; Automation ; Cardiac ; Diagnostic Radiology ; Feasibility Studies ; Female ; Heart Ventricles - pathology ; Humans ; Imaging ; Internal Medicine ; Interventional Radiology ; Magnetic Resonance Angiography - methods ; Magnetic resonance imaging ; Magnetic Resonance Imaging, Cine ; Magnetic Resonance Spectroscopy ; Male ; Medicine ; Medicine &amp; Public Health ; Methods ; Middle Aged ; Myocardium - pathology ; Neuroradiology ; Observer Variation ; Radiology ; Reproducibility of Results ; Stroke Volume - physiology ; Ultrasound ; Ventricular Dysfunction, Left - pathology ; Ventricular Dysfunction, Left - physiopathology</subject><ispartof>European radiology, 2016-05, Vol.26 (5), p.1503-1511</ispartof><rights>European Society of Radiology 2015</rights><rights>European Society of Radiology 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-d1886be4eb286d767c1c55a8c6038d0256d223a6369c796a225f4006f8b96c763</citedby><cites>FETCH-LOGICAL-c372t-d1886be4eb286d767c1c55a8c6038d0256d223a6369c796a225f4006f8b96c763</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26267520$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Varga-Szemes, Akos</creatorcontrib><creatorcontrib>Muscogiuri, Giuseppe</creatorcontrib><creatorcontrib>Schoepf, U. Joseph</creatorcontrib><creatorcontrib>Wichmann, Julian L.</creatorcontrib><creatorcontrib>Suranyi, Pal</creatorcontrib><creatorcontrib>De Cecco, Carlo N.</creatorcontrib><creatorcontrib>Cannaò, Paola M.</creatorcontrib><creatorcontrib>Renker, Matthias</creatorcontrib><creatorcontrib>Mangold, Stefanie</creatorcontrib><creatorcontrib>Fox, Mary A.</creatorcontrib><creatorcontrib>Ruzsics, Balazs</creatorcontrib><title>Clinical feasibility of a myocardial signal intensity threshold-based semi-automated cardiac magnetic resonance segmentation method</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Objectives To assess the accuracy and efficiency of a threshold-based, semi-automated cardiac MRI segmentation algorithm in comparison with conventional contour-based segmentation and aortic flow measurements. Methods Short-axis cine images of 148 patients (55 ± 18 years, 81 men) were used to evaluate left ventricular (LV) volumes and mass (LVM) using conventional and threshold-based segmentations. Phase-contrast images were used to independently measure stroke volume (SV). LV parameters were evaluated by two independent readers. Results Evaluation times using the conventional and threshold-based methods were 8.4 ± 1.9 and 4.2 ± 1.3 min, respectively ( P  &lt; 0.0001). LV parameters measured by the conventional and threshold-based methods, respectively, were end-diastolic volume (EDV) 146 ± 59 and 134 ± 53 ml; end-systolic volume (ESV) 64 ± 47 and 59 ± 46 ml; SV 82 ± 29 and 74 ± 28 ml (flow-based 74 ± 30 ml); ejection fraction (EF) 59 ± 16 and 58 ± 17 %; and LVM 141 ± 55 and 159 ± 58 g. Significant differences between the conventional and threshold-based methods were observed in EDV, ESV, and LVM mesurements; SV from threshold-based and flow-based measurements were in agreement ( P  &gt; 0.05) but were significantly different from conventional analysis ( P  &lt; 0.05). Excellent inter-observer agreement was observed. Conclusions Threshold-based LV segmentation provides improved accuracy and faster assessment compared to conventional contour-based methods. 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Joseph</au><au>Wichmann, Julian L.</au><au>Suranyi, Pal</au><au>De Cecco, Carlo N.</au><au>Cannaò, Paola M.</au><au>Renker, Matthias</au><au>Mangold, Stefanie</au><au>Fox, Mary A.</au><au>Ruzsics, Balazs</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical feasibility of a myocardial signal intensity threshold-based semi-automated cardiac magnetic resonance segmentation method</atitle><jtitle>European radiology</jtitle><stitle>Eur Radiol</stitle><addtitle>Eur Radiol</addtitle><date>2016-05-01</date><risdate>2016</risdate><volume>26</volume><issue>5</issue><spage>1503</spage><epage>1511</epage><pages>1503-1511</pages><issn>0938-7994</issn><eissn>1432-1084</eissn><abstract>Objectives To assess the accuracy and efficiency of a threshold-based, semi-automated cardiac MRI segmentation algorithm in comparison with conventional contour-based segmentation and aortic flow measurements. Methods Short-axis cine images of 148 patients (55 ± 18 years, 81 men) were used to evaluate left ventricular (LV) volumes and mass (LVM) using conventional and threshold-based segmentations. Phase-contrast images were used to independently measure stroke volume (SV). LV parameters were evaluated by two independent readers. Results Evaluation times using the conventional and threshold-based methods were 8.4 ± 1.9 and 4.2 ± 1.3 min, respectively ( P  &lt; 0.0001). LV parameters measured by the conventional and threshold-based methods, respectively, were end-diastolic volume (EDV) 146 ± 59 and 134 ± 53 ml; end-systolic volume (ESV) 64 ± 47 and 59 ± 46 ml; SV 82 ± 29 and 74 ± 28 ml (flow-based 74 ± 30 ml); ejection fraction (EF) 59 ± 16 and 58 ± 17 %; and LVM 141 ± 55 and 159 ± 58 g. Significant differences between the conventional and threshold-based methods were observed in EDV, ESV, and LVM mesurements; SV from threshold-based and flow-based measurements were in agreement ( P  &gt; 0.05) but were significantly different from conventional analysis ( P  &lt; 0.05). Excellent inter-observer agreement was observed. Conclusions Threshold-based LV segmentation provides improved accuracy and faster assessment compared to conventional contour-based methods. Key Points • Threshold-based left ventricular segmentation provides time-efficient assessment of left ventricular parameters • The threshold-based method can discriminate between blood and papillary muscles • This method provides improved accuracy compared to aortic flow measurements as a reference</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>26267520</pmid><doi>10.1007/s00330-015-3952-4</doi><tpages>9</tpages></addata></record>
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source Springer Nature
subjects Accuracy
Algorithms
Automation
Cardiac
Diagnostic Radiology
Feasibility Studies
Female
Heart Ventricles - pathology
Humans
Imaging
Internal Medicine
Interventional Radiology
Magnetic Resonance Angiography - methods
Magnetic resonance imaging
Magnetic Resonance Imaging, Cine
Magnetic Resonance Spectroscopy
Male
Medicine
Medicine & Public Health
Methods
Middle Aged
Myocardium - pathology
Neuroradiology
Observer Variation
Radiology
Reproducibility of Results
Stroke Volume - physiology
Ultrasound
Ventricular Dysfunction, Left - pathology
Ventricular Dysfunction, Left - physiopathology
title Clinical feasibility of a myocardial signal intensity threshold-based semi-automated cardiac magnetic resonance segmentation method
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