A pathological condition possibly caused by spontaneous trichotecene poisoning in Brahma poultry: first report

Trichotecene poisoning in poultry can cause oral lesions, haemorrhages, depletion and necrosis in the lymphopoetic organs and death. Spontaneous poisonings with these toxins are rarely described. This paper describes the spontaneous poisoning of two Brahma chickens with T-2 toxin, diacetoxyscirpenol...

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Bibliographic Details
Published in:Avian pathology 2004-06, Vol.33 (3), p.328-331
Main Authors: Konjević, Dean, Srebočan, Emil, Gudan, Andrea, Lojkić, Ivana, Severin, Krešimir, Sokolović, Marijana
Format: Article
Language:English
Subjects:
Food
Pathology
Poultry
Toxins
Online Access:Get full text
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Summary:Trichotecene poisoning in poultry can cause oral lesions, haemorrhages, depletion and necrosis in the lymphopoetic organs and death. Spontaneous poisonings with these toxins are rarely described. This paper describes the spontaneous poisoning of two Brahma chickens with T-2 toxin, diacetoxyscirpenol and deoxynivalenol. Two out of 10 chickens died under signs of depression and loss of appetite. Histopathological analysis revealed vacuolar dystrophy of the liver, necrosis and depletion of lymphocyte in the bursa of Fabricius as well as multiple necroses in the glandular stomach and gut. Even though quantities of 0.70 mg/kg T-2 in the food together with 0.50 mg/kg diacetoxyscirpenol significantly differ from the median lethal dose for chickens reported in literature (4.97 mg/kg), parasitological, virological and histopathological results indicate trichotecenes as the causative agents of this pathological condition. [PUBLICATION ABSTRACT]
ISSN:0307-9457
1465-3338
DOI:10.1080/0307945742000220714