Pre-awakening diastolic hypotension in treated hypertensive patients: prevalence and predictors

In the pre-awakening hours, diastolic blood pressure (DBP) is normally at its lowest, and diastolic hypotension is a risk factor for cardiac ischemia. We investigated pre-awakening DBP values and its predictors in treated hypertensive patients who underwent ambulatory blood pressure monitoring. The...

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Bibliographic Details
Published in:Journal of human hypertension 2016-05, Vol.30 (5), p.322-327
Main Authors: Zheng, K H, Serné, E H, Kooter, A J, Smulders, Y M
Format: Article
Language:English
Subjects:
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Aged
Antihypertensives
Blood pressure
Circadian Rhythm
Development and progression
Diabetes mellitus
Diastole
Diastole (Cardiac cycle)
Epidemiology
Female
Health Administration
Humans
Hypertension
Hypertension - physiopathology
Hypotension
Hypotension - epidemiology
Ischemia
Male
Measurement
Medicine
Medicine & Public Health
Middle Aged
Netherlands - epidemiology
original-article
Prevalence
Public Health
Regulation
Retrospective Studies
Risk factors
Sleep - physiology
Vascular diseases
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Summary:In the pre-awakening hours, diastolic blood pressure (DBP) is normally at its lowest, and diastolic hypotension is a risk factor for cardiac ischemia. We investigated pre-awakening DBP values and its predictors in treated hypertensive patients who underwent ambulatory blood pressure monitoring. The pre-awakening period was defined as the 3-h period ending 1 h before awakening (most frequently 03:00–06:00). In 269 included subjects, office DBP was 86.4±12.0 mm Hg, 24-h DBP was 78.6±9.6 mm Hg, mean pre-awakening DBP was 70.3±10.9 mm Hg, and trough pre-awakening DBP was 62.5±11.2 mm Hg. Half of the patients (51%) had a mean pre-awakening DBP
ISSN:0950-9240
1476-5527
DOI:10.1038/jhh.2015.80