Infective endocarditis in diabetic and non-diabetic patients

We compared clinical, microbiological, and prognostic characteristics of infective endocarditis in patients with and without diabetes mellitus. In 1987-1996, 213 patients with definite or possible infective endocarditis were included, of which 39 (18%) had diabetes mellitus. Diabetic patients were o...

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Bibliographic Details
Published in:Scandinavian journal of infectious diseases 2004-12, Vol.36 (11-12), p.795-798
Main Authors: Bishara, Jihad, Peled, Nir, Samra, Zmira, Sagie, Alex, Leibovici, Leonard, Pitlik, Silvio
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Cardiology. Vascular system
Diabetes Complications - epidemiology
Diabetes Complications - microbiology
Diabetes Complications - mortality
Diabetes Mellitus - epidemiology
Diabetes Mellitus - mortality
Diabetes. Impaired glucose tolerance
Endocardial and cardiac valvular diseases
Endocarditis, Bacterial - complications
Endocarditis, Bacterial - epidemiology
Endocarditis, Bacterial - mortality
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Female
Heart
Heart Valves - microbiology
Hospital Mortality
Humans
Israel - epidemiology
Male
Medical Records
Medical sciences
Middle Aged
Prognosis
Staphylococcus aureus
Staphylococcus aureus - isolation & purification
Survival Rate
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Summary:We compared clinical, microbiological, and prognostic characteristics of infective endocarditis in patients with and without diabetes mellitus. In 1987-1996, 213 patients with definite or possible infective endocarditis were included, of which 39 (18%) had diabetes mellitus. Diabetic patients were older than non-diabetic (median age of 71 vs 65 y, respectively; p=0.04), had more aortic valve and less mitral valve involvement (71% vs 27%, and 21% vs 62%; p=0.004). There was no significant difference in the frequency of Staphylococcus aureus involvement between the 2 groups (21% in diabetic vs 20% in non-diabetic group; p=ns). On multivariate analysis diabetes mellitus was not found to be an independent factor for mortality. Unlike other infections diabetes mellitus does not significantly affect clinical and microbiological features, and outcome of infective endocarditis.
ISSN:0036-5548
1651-1980
DOI:10.1080/00365540410025384