Histopathologic findings of spontaneous osteonecrosis of the knee at an early stage: a case report

We histopathologically examined a surgically resected full specimen obtained from an early-stage spontaneous osteonecrosis of the knee (SPONK). On a mid-coronal cut section of the resected medial femoral condyle, a linear fracture line paralleling the subchondral bone endplate was found. Histopathol...

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Bibliographic Details
Published in:Skeletal radiology 2016-05, Vol.45 (5), p.713-716
Main Authors: Hatanaka, Hiroyuki, Yamamoto, Takuaki, Motomura, Goro, Sonoda, Kazuhiko, Iwamoto, Yukihide
Format: Article
Language:English
Subjects:
Aged
Bones
Case Report
Diagnosis, Differential
Disease Progression
Early Diagnosis
Humans
Imaging
Knee Joint - diagnostic imaging
Knee Joint - pathology
Magnetic Resonance Imaging - methods
Male
Medicine
Medicine & Public Health
Necrosis
Nuclear Medicine
Orthopedics
Osteonecrosis - diagnostic imaging
Osteonecrosis - pathology
Pathology
Radiology
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Summary:We histopathologically examined a surgically resected full specimen obtained from an early-stage spontaneous osteonecrosis of the knee (SPONK). On a mid-coronal cut section of the resected medial femoral condyle, a linear fracture line paralleling the subchondral bone endplate was found. Histopathologically, prominent callus formation was seen comprising of reactive woven bone and granulation tissue on both sides of the fracture. Fracture-related bone debris was focally observed at the osteochondral side of the fracture. Definitive features of antecedent bone infarction such as creeping substitution and bone marrow necrosis were not detected. These findings suggested that SPONK was the result of a subchondral fracture rather than primary osteonecrosis.
ISSN:0364-2348
1432-2161
DOI:10.1007/s00256-016-2328-4