Antimycotic activity of the essential oil of Artemisia nilagirica

During screening of essential oils isolated from leaves of 10 angiospermic taxa against dermatophytes Epidermophyton floccosum and Trichophyton violaceum, the essential oil of Artemisia nilagirica was found to possess complete antidermatophytic activity by the poisoned food technique. The minimum in...

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Bibliographic Details
Published in:Flavour and fragrance journal 2001-01, Vol.16 (1), p.61-63
Main Authors: Kishore, N., Dubey, N. K., Chansouria, J. P. N.
Format: Article
Language:English
Subjects:
antifungal agents
antimycotic
Artemisia nilagirica
Biological and medical sciences
Epodermophyton floccosum
essential oil
General pharmacology
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Trichophyton violaceum
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Summary:During screening of essential oils isolated from leaves of 10 angiospermic taxa against dermatophytes Epidermophyton floccosum and Trichophyton violaceum, the essential oil of Artemisia nilagirica was found to possess complete antidermatophytic activity by the poisoned food technique. The minimum inhibitory concentration of the oil was found to be 200 ppm. It was fungistatic in nature and had a broad fungitoxic spectrum. An ointment of the essential oil prepared in polyethylene glycol showed pronounced efficacy as a herbal antifungal agent against dermatomycosis induced in guinea‐pigs within 14 days of application. The oil was standardized on the basis of its different physico chemical properties, such as specific gravity, specific rotation, refractive index, acid value, saponification value, carbonyl percentage and phenolic content. Copyright © 2001 John Wiley & Sons, Ltd.
ISSN:0882-5734
1099-1026
DOI:10.1002/1099-1026(200101/02)16:1<61::AID-FFJ946>3.0.CO;2-V