A study of margin width and local recurrence in breast conserving therapy for invasive breast cancer

Abstract Purpose Debate continues on what is an adequate margin width to define a clear margin and whether there is a need to excise pectoral fascia or remove skin in breast conserving surgery. This study set out to provide answers to these questions. Patients and methods 1411 patients with invasive...

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Bibliographic Details
Published in:European journal of surgical oncology 2016-05, Vol.42 (5), p.657-664
Main Authors: Dixon, J.M, Thomas, J, Kerr, G.R, Williams, L.J, Dodds, C, Kunkler, I.H, Macaskill, E.J
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Breast conserving surgery
Breast Neoplasms - pathology
Breast Neoplasms - radiotherapy
Breast Neoplasms - surgery
Combined Modality Therapy
Female
Hematology, Oncology and Palliative Medicine
Humans
Invasive breast cancer
Local recurrence
Lymphatic Metastasis
Margin width
Mastectomy, Segmental - methods
Middle Aged
Neoplasm Grading
Neoplasm Invasiveness
Neoplasm Recurrence, Local
Surgery
Survival Rate
Treatment Outcome
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Summary:Abstract Purpose Debate continues on what is an adequate margin width to define a clear margin and whether there is a need to excise pectoral fascia or remove skin in breast conserving surgery. This study set out to provide answers to these questions. Patients and methods 1411 patients with invasive breast cancer were treated by breast conserving surgery and post-operative whole breast radiotherapy from January 2000 to December 2005. Distance from each margin to any in situ or invasive cancer was measured and recorded. If full thickness of breast tissue was removed no re excision of anterior and posterior margins was performed even if disease was
ISSN:0748-7983
1532-2157
DOI:10.1016/j.ejso.2016.02.008