Prenatal sonographic ultrasound predictors for the outcome in fetal gastroschisis: a retrospective analysis

Purpose To identify predictive ultrasound signs for unfavorable outcome in fetal gastroschisis (GS). Methods This is a retrospective cohort study among pregnant women with the prenatal diagnosis of GS between 1998 and 2011 at the University of Wuerzburg, Germany. Analysis included prenatal ultrasoun...

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Bibliographic Details
Published in:Archives of gynecology and obstetrics 2016-05, Vol.293 (5), p.1001-1006
Main Authors: Stüber, Tanja Nadine, Frieauff, Eric, Weiß, Claire, Zollner, Ursula, Wöckel, Achim, Meyer, Thomas, Rehn, Monika
Format: Article
Language:English
Subjects:
Adult
Amniotic Fluid - diagnostic imaging
Child
Cohort Studies
Endocrinology
Female
Gastroschisis - diagnosis
Gastroschisis - surgery
Germany
Gestational Age
Gynecology
Human Genetics
Humans
Infant, Newborn
Intensive Care Units, Neonatal
Maternal-Fetal Medicine
Medicine
Medicine & Public Health
Obstetrics/Perinatology/Midwifery
Pregnancy
Prenatal development
Prenatal Diagnosis
Prognosis
Retrospective Studies
Treatment Outcome
Ultrasonic imaging
Ultrasonography, Prenatal
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Summary:Purpose To identify predictive ultrasound signs for unfavorable outcome in fetal gastroschisis (GS). Methods This is a retrospective cohort study among pregnant women with the prenatal diagnosis of GS between 1998 and 2011 at the University of Wuerzburg, Germany. Analysis included prenatal ultrasound scans, neonatal intensive care unit (NICU) records, and pediatric records. The collected variables included maternal and fetal demographics, as well as an analysis of predictors for unfavorable fetal outcome. Unfavorable outcome was defined by more than 2 postnatal surgical interventions, intestinal resections, and long time to oral feeding (≥4 weeks). Results 35 cases of fetal GS were diagnosed, whereby 23 cases met the inclusion criteria and were evaluated by prenatal ultrasound and postnatal outcome. Based on the postnatal situation, 15 patients were classified in a good prognosis group and 8 patients in a poor prognosis group. Fetuses with poor prognosis were presented later during pregnancy (21.1 ± 6 vs. 26.9 ± 5.3 weeks; p  
ISSN:0932-0067
1432-0711
DOI:10.1007/s00404-015-3936-2