Significance of chemokine and chemokine receptors in head and neck squamous cell carcinoma: A critical review

Highlights • We reviewed current knowledge in the literature on OSCC and chemokines. • The chemokine and chemokine/receptor system play key roles on oral tumogigenesis. • Therapies directed at chemokines and its receptors may be a novel approach in the treatment of oral cancer.

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Bibliographic Details
Published in:Oral oncology 2016-05, Vol.56, p.8-16
Main Authors: da Silva, Janine Mayra, Soave, Danilo Figueiredo, Moreira dos Santos, Tálita Pollyanna, Batista, Aline Carvalho, Russo, Remo Castro, Teixeira, Mauro Martins, Silva, Tarcília Aparecida da
Format: Article
Language:English
Subjects:
Carcinoma, Squamous Cell - metabolism
Chemokines
Chemokines - metabolism
Head and Neck Neoplasms - metabolism
Head and neck squamous cell carcinoma
Hematology, Oncology and Palliative Medicine
Humans
Inflammation
Otolaryngology
Receptors, Chemokine - metabolism
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Description
Summary:Highlights • We reviewed current knowledge in the literature on OSCC and chemokines. • The chemokine and chemokine/receptor system play key roles on oral tumogigenesis. • Therapies directed at chemokines and its receptors may be a novel approach in the treatment of oral cancer.
ISSN:1368-8375
1879-0593
DOI:10.1016/j.oraloncology.2016.02.016