Maternal serum atrial natriuretic peptide (ANP) and brain-type natriuretic peptide (BNP) levels in gestational diabetes mellitus

Objective: The aim of the study is to evaluate maternal serum atrial natriuretic peptide (ANP) and brain-type natriuretic peptide (BNP) levels in patients with getational diabetes mellitus compared with a control group. Methods: We have measured maternal serum ANP and BNP levels in 35 otherwise heal...

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Published in:The journal of maternal-fetal & neonatal medicine 2016-01, Vol.29 (15), p.2526-2529
Main Authors: Yuksel, Mehmet Aytac, Alici Davutoglu, Ebru, Temel Yuksel, Ilkbal, Kucur, Mine, Ekmekci, Hakan, Balci Ekmekci, Ozlem, Uludag, Sezin, Uludag, Seyfettin, Madazli, Riza
Format: Article
Language:English
Subjects:
Adult
Atrial Natriuretic Factor - blood
Atrial natriuretic peptide
Biomarkers - blood
brain-type natriuretic peptide
Cross-Sectional Studies
Diabetes, Gestational - blood
Female
gestational diabetes mellitus
Humans
Natriuretic Peptide, Brain - blood
Pregnancy
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Summary:Objective: The aim of the study is to evaluate maternal serum atrial natriuretic peptide (ANP) and brain-type natriuretic peptide (BNP) levels in patients with getational diabetes mellitus compared with a control group. Methods: We have measured maternal serum ANP and BNP levels in 35 otherwise healthy and 45 gestational diabetic women between gestational week 24 and 28 referred to our unit in a cross-sectional study. Independent samples t-test or the Mann-Whitney U-test was used for comparison of two groups where appropriate. Results: Mean maternal serum homeostasis model assessment of insulin resistance (HOMA-IR), HbA1c, fasting glucose and insulin levels in gestational diabetes mellitus (GDM) group were significantly higher than the control group (p 
ISSN:1476-7058
1476-4954
DOI:10.3109/14767058.2015.1092958