The role of margins in extremity soft tissue sarcoma

For extremity soft tissue sarcomas, limb salvage is now standard of care. The extent of surgical margins is balanced with functionality of the resected limb. Although negative margins are the goal, the necessary width is unclear. Additional considerations for margin adequacy include presence of anat...

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Bibliographic Details
Published in:Journal of surgical oncology 2016-03, Vol.113 (3), p.333-338
Main Authors: Byerly, Saskya, Chopra, Shefali, Nassif, Nader A., Chen, Peter, Sener, Stephen F., Eisenberg, Burton L., Tseng, William W.
Format: Article
Language:English
Subjects:
Extremities - pathology
Extremities - surgery
extremity
Humans
Limb Salvage
margins
Neoadjuvant Therapy - methods
Neoplasm Recurrence, Local - prevention & control
Neoplasm, Residual - prevention & control
Sarcoma - pathology
Sarcoma - prevention & control
Sarcoma - surgery
Soft Tissue Neoplasms - pathology
Soft Tissue Neoplasms - prevention & control
Soft Tissue Neoplasms - surgery
soft tissue sarcoma
Surgical Procedures, Operative - methods
Surgical Procedures, Operative - standards
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Summary:For extremity soft tissue sarcomas, limb salvage is now standard of care. The extent of surgical margins is balanced with functionality of the resected limb. Although negative margins are the goal, the necessary width is unclear. Additional considerations for margin adequacy include presence of anatomic barriers such as fascia and periosteum, proximity of critical structures, receipt of adjuvant and neoadjuvant therapies, and histologic subtype. Multidisciplinary team discussion is critical for treatment planning. J. Surg. Oncol. 2016;113:333–338. © 2015 Wiley Periodicals, Inc.
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.24112