Esophageal motility after peroral endoscopic myotomy for achalasia

Background Peroral endoscopic myotomy (POEM) has been introduced as a novel endoscopic treatment for achalasia. The aim of this work is to assess the changes in esophageal motility caused by POEM in patients with achalasia. Methods Forty-one patients with achalasia underwent POEM from September 2012...

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Bibliographic Details
Published in:Journal of gastroenterology 2016-05, Vol.51 (5), p.458-464
Main Authors: Hu, Yue, Li, Meng, Lu, Bin, Meng, Lina, Fan, Yihong, Bao, Haibiao
Format: Article
Language:English
Subjects:
Abdominal Surgery
Achalasia
Adolescent
Adult
Aged
Care and treatment
Colorectal Surgery
Deglutition - physiology
Endoscopy
Esophageal Achalasia - surgery
Esophagoscopy - methods
Female
Follow-Up Studies
Gastroenterology
Gastrointestinal Motility - physiology
Hepatology
Humans
Male
Manometry
Medicine
Medicine & Public Health
Middle Aged
Original Article—Alimentary Tract
Peristalsis - physiology
Pressure
Prospective Studies
Surgical Oncology
Young Adult
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Summary:Background Peroral endoscopic myotomy (POEM) has been introduced as a novel endoscopic treatment for achalasia. The aim of this work is to assess the changes in esophageal motility caused by POEM in patients with achalasia. Methods Forty-one patients with achalasia underwent POEM from September 2012 to November 2014. Esophageal motility of all patients was evaluated preoperatively and 1 month after POEM utilizing high-resolution manometry, which was performed with ten water swallows, ten steamed bread swallows, and multiple rapid swallows (MRS). Results In single swallows, including liquid swallows and bread swallows, all the parameters of lower esophagus sphincter resting pressure (LESP), 4-s integrated relaxation pressure (4sIRP), and intra-bolus pressure (IBP) were decreased between pre- and post-POEM patients (all p   0.05). In liquid swallows, the Eckardt score of subtype II patients decreased with DCI, and distal esophageal peristaltic amplitude after POEM was significantly lower compared with those showing increased values of those two parameters ( p  
ISSN:0944-1174
1435-5922
DOI:10.1007/s00535-015-1123-7